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20 July 2020 | Story Leonie Bolleurs | Photo Supplied
The view from one of the offices in the Marion Island research station, with fresh snowfall in the interior of the island in the background.

Liezel Rudolph, lecturer and researcher in the Department of Geography at the University of the Free State (UFS), is strongly convinced that the Southern Hemisphere’s past glacial cycles will provide valuable insights to help predict and prepare for future climate change. Climate is changing fast and the magnitude of change we have seen over the last 30 years has taken a hundred or several hundred years to occur in the past. 

It is not only temperatures that are rising, but changes in wind patterns, rain cycles, oceanic circulation, etc., are also observed. As we do not know how the earth will respond or adapt to such rapid and drastic changes in climatic patterns, this poses various threats.

Link between landscape responses and climate change

Rudolph focuses her research on reconstructing the past climate of Marion Island. 

She had the wonderful opportunity to visit the island for the past three years with study and project leaders, Profs Werner Nel from the University of Fort Hare and David Hedding from UNISA, she departed on a ship to Marion Island to conduct fieldwork.They published their research findings of fieldwork conducted in 2017 and 2018.  

According to Rudolph, research in Antarctica, the Southern Ocean, and islands such as Marion Island is very important. South Africa is the only African country with research stations that have the ability to explore these regions.

“Marion Island has many landforms that could only have been created by glacial erosional or depositional processes, with glaciers currently absent from the island. To determine when the island was last in a full glacial period, we date the formation ages of these landforms.”

“In the short time we have been visiting the island, it was impossible to notice any drastic changes in the island climate. That is why we use these very old landforms to tell us more about periods before humans visited the island,” she says. 

Rudolph believes that understanding the link between landscape responses and climate change of the past can help to better predict some of the climate change processes that are currently threatening the planet.

“There’s a principle in geography called ‘uniformitarianism’, whereby we assume that the earth-surface processes we observe today, are the same as those that have been active in the past,” says Rudolph.

As scientists, they thus look at evidence of past geomorphic processes (which remain in the landscape in various forms, e.g. residual landforms, stratigraphic sequences, etc.) to piece together what the past climate was like. In the same way, they also use this principle to predict how certain earth processes will change in the future, along with climate changes.

“In return, we understand how the climate and the earth’s surface interact, and we can better predict how the earth will respond to climate change,” Rudolph adds. 

Society to play its part in climate change

In the long run, we as the public should play our part in readying society for the effects of climate change. 

Rudolph says society can play a positive role in terms of climate change by educating themselves with unbiased, scientifically sound information on the true state of climate change and by responding within their own spheres of influence.

“Don’t leave everything up to politicians and policy. As the public, you can start to make progress by assessing the effects that climate change may have on your industry, business or society, and strategise on how to adapt your processes to deal with these changes.”

“Be responsible with our natural resources, reduce your waste, support local businesses that are sustainable, and volunteer at a local environmental protection/clean-up organisation. All the small efforts will eventually add up to substantial change,” she says. 

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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