04 September 2026 | Story Andre Damons | Photo Andre Damons and Kaleidoscope
Prof Matsabisa 22
Prof Motlalepula Matsabisa, renowned African traditional medicine expert and pharmacology researcher at the University of the Free State, contribution to African traditional medicine research has been recognised with the prestigious Hamilton Naki Award from the National Research Foundation (NRF).

When Prof Motlalepula Matsabisa began researching African traditional medicine, scepticism was never far away. Today, after decades of perseverance, scientific research and an unwavering belief in his work, his contribution has been recognised with the prestigious Hamilton Naki Award from the National Research Foundation (NRF).

For Prof Matsabisa, renowned African traditional medicine expert and pharmacology researcher at the University of the Free State (UFS), the recognition is more than a prestigious accolade. It is a powerful affirmation of a career built on persistence, consistency and the courage to pursue a path that many once dismissed.

The Hamilton Naki Award, named after Hamilton Naki, a self-taught surgeon who trained generations of medical students in surgical techniques, was awarded to him on Thursday evening (3 September) as part of the annual NRF Awards. The Hamilton Naki Award honours individuals for advancing their careers in science and achieving world-class research performance despite considerable challenges – a fitting tribute to Prof Matsabisa who refused to give up when others questioned whether his field belonged in science.

 

A fitting recognition for a career against the odds

“I feel really honoured to receive such a prestigious award. I did not expect recognition at this level. It shows that all my efforts and struggles to do good science and research under not-so conducive environments were noticed and found worthy of this award.

“What makes this award even more special is the fact that it depicts success against all odds. That means a lot to me. Starting research in traditional medicines with many sceptics who called this, and continue to call this, pseudo-science is worthy of all the struggles I had. My perseverance, hard work, consistency and belief eventually paid off,” he says.

Attending the awards ceremony, a proud Prof Vasu Reddy, Deputy Vice-Chancellor: Research, Innovation and Postgraduate Studies, remarked: “We celebrate a scholar whose perseverance transformed scepticism into internationally recognised scientific excellence. Prof Matsabisa’s achievement reflects the power of rigorous research to validate and advance indigenous knowledge systems.

“This prestigious Hamilton Naki Award affirms the value of research that challenges convention while maintaining the highest scientific standards. His career demonstrates that impactful research begins with courage, conviction, and a commitment to societal benefit.”

The road was far from easy because traditional medicine research was, and in some quarters remains, labelled as “pseudo-science”. Yet instead of allowing the criticism to define his work, Prof Matsabisa used it as motivation to build a strong scientific foundation for research into African traditional medicines.

While at the University of Cape Town and Groote Schuur Hospital, he approached his Head of Department in Pharmacology about pursuing research into traditional medicines. “I recall him telling me, ‘Nobody knows and understands traditional medicine – I can allow you to pursue your research and studies if you teach me about traditional medicine.’ I had to teach myself while at the same time, introduce a new subject at the time nobody believed in.

“This award resonates with me. It is an award that I feel truly reflects on my achievements. A person who struggled to get research accepted by peers is now the best-performing research in the (UFS) Faculty of Health Science and a shining star for the UFS in traditional medicines research nationally and internationally,” says Prof Matsabisa.

 

World renowned

Today, Prof Matsabisa, Director of the Department of Pharmacology and the Research Director for the African Medicines Innovations and Technologies Development Platform (AMITD) at the UFS, is a distinguished researcher and recognised globally as a leading expert in traditional medicine. In 2025, Prof Matsabisa was elected a co-chairperson of the World Health Organization (WHO) Global Traditional Medicine Summit steering committee. In the same year, he was appointed to the World Health Organization (WHO) Strategic and Technical Advisory Group (the “STAG”) on Traditional, Complementary and Integrative Medicine, where he leads the Regulation subgroup of the STAG and is as well a visiting professor of Pharmacology to the Busitema University in Uganda. Prof Matsabisa is a member of the Advisory Committee of the Science Summit, convened annually alongside the United Nations General Assembly. He is a member of the Complementary and Alternative Medicines Task Force Plant Medicines Task Force for Medical Therapies Commission of the International League for Epilepsy (ILAE).

He was previously also appointed to serve on the WHO Global Centre for Traditional Medicine Editorial Board/Evidence Task Force. During the height of the COVID-19 pandemic, Prof Matsabisa led Africa’s fight against the pandemic with his appointment as chairperson of the WHO Regional Expert Advisory Committee on Traditional Medicines for COVID-19. He was a WHO AFRO expert: WHO 1st Global Traditional Medicine Summit External Advisory Group/ alongside the G20 Health Ministerial Meeting and currently also the co-chair of the WHO 2nd Global Traditional Medicines Summit Steering Committee.

 

Research areas

His areas of specialisation are in Pharmacology and Pharmacology of Traditional Medicines, in Drug Discovery and Development, the formulation research of traditional medicinal products to proprietary finished final products. The research encompasses all value chains of new drug research, basic science research, discovery, development, pharmaceutical research to clinical trials.

The focus of his research work is on discovery and development of new drugs and medicines based on traditional and herbal African medicines. The research entails looking at the safety, efficacy and quality of traditional medicines for select diseases such as diabetes, hypertension, cancer, malaria and neurodegenerative disease such as Alzheimer’s disease.

 

A journey built on people

Despite the personal nature of the award, Prof Matsabisa is quick to point to the people who helped make his journey possible. He thanked the NRF for what he describes as a “very fitting recognition”, and which has supported him along the way, from their first research grant (R70 000 instead of R700 000 which he applied for, before granting him the full amount) and beyond. He also thanked the communities, knowledge holders and traditional health practitioners who placed their trust in him to work with their knowledge. Their contribution, he says, cannot be separated from the research. I thank all my staff, researchers and scientists who walked with through this forest of doubt and difficulty and support me course and scientific work without by fazed to be pseudo scientists.

He also expressed his gratitude to UFS management for supporting his work, particularly at times when there were doubts about the value of traditional medicine research. And then there is his family, whom he credits with providing the support that helped him continue his work and reminding him of the importance of what he does for society and the world.

“To all those that struggle, that are not seen nor recognised, please don't give up,” he says. He believes that people can overcome the odds by following three principles: persevere, believe in yourself and be yourself; deliver on your promises; and be a people's person.

For Prof Matsabisa, academic qualifications and achievements never change who he is as a person. He believes researchers must be able to move between worlds – to speak to academics at their level, but also to sit with people who are poor, vulnerable, suffering or homeless and engage with them with the same respect and humanity.

 

A message to emerging researchers

To emerging researchers, scientists and academics, Prof Matsabisa says: “Believe in yourself, stay positive, and do not be distracted by passing trends or the doubts of others. The most meaningful breakthroughs are often achieved by those who persevere when success seems distant. Progress is built through consistent efforts and an unwavering commitment to your purpose.

“As the Chinese proverb reminds us, ‘It is better to light a candle than curse the darkness,’ and the Latin saying ‘Constant dripping drops of water hollows out a stone’ teaches that small, steady actions can achieve extraordinary results over time. Keep moving forward, even when the odds seem against you. Perseverance, resilience and belief in your work will ultimately open doors that once seemed closed.”

Prof Reddy observed that the University of the Free State is proud to see African-led innovation and discovery receive global recognition through Prof Matsabisa’s work. “Prof Matsabisa exemplifies how research excellence can bridge modern science, community knowledge, and real-world health solutions. This award is not only a personal milestone but also a significant moment for African scholarship and knowledge advancement.”

Dr Zurika Murray, a researcher in Behavioural Genetics in the Department of Genetics, and Dr Cobus Van Breda, Programme Director of the Science-for-the-Future Unit and Manager of the Sci-Ed Science Education Centre, were also announced as winners in their respected categories. Dr Murray was the recipient of the prestigious Research Excellence Award for Next-Generation Researchers, while Dr Van Breda won the Societal Impact Award.

• Read more about Prof Matsabisa’s work here:



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