Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
08 June 2020 | Story Valentino Ndaba | Photo Sonia Small
Prof Francis Petersen is one of the leaders in a prestigious international panel for a COVID-19 webinar involving Uganda, the Netherlands, and Morocco.

 

Webinar details
Date: Wednesday, 10 June 2020
Time: 13:00 South African time (14:00 East African Standard Time)

Webinar link: https://www.ruforum.org/introductory-note-webinar-1
To participate register here

University leaders from Africa and beyond will take part in a Regional Universities Forum for Capacity Building in Agriculture (RUFORUM) webinar on Wednesday, 10 June, to look at universities’ responses to the COVID-19 pandemic. Prof Francis Petersen, Rector and Vice-Chancellor of the University of the Free State, will be one of four panellists who will be the main speakers of the day. He is the only panellist from South Africa. 

Prof Petersen will participate alongside university leaders such as Prof Arthur Mol, Rector Magnificus of Wageningen University and Research in the Netherlands, Mr Hicham el Habti, Secretary General at the Mohammed VI Polytechnique University (UM6P) in Morocco, as well as Prof Barnabas Nawangwe, Vice-Chancellor of the Makerere University in Uganda. 

Getting together with other university leaders from the continent and abroad, speakers will share insights from their respective countries in dealing with the pandemic. The webinar takes place on 10 June 2020 at 13:00 South African time (14:00 East African Standard Time)

RUFORUM is a consortium of 46 universities in Eastern, Central, Western, and Southern Africa mandated to oversee graduate training and networks of specialisation in the countries and universities where it works. 

What is the webinar about?
The RUFORUM webinar titled ‘Learning from a crisis: University leaders’ response to the COVID-19 Pandemic', aims to tackle issues such as the immediate needs of universities, including staff realignment, dealing with the digital divide in the student community, institutional finance for operations and innovations in a changing landscape, and international students in a crisis moment. 

This webinar provides a great opportunity to galvanise collective responses from university leaders on this pandemic. It brings together universities from within and outside Africa on lessons learnt in confronting the immediate challenges and how they are resetting for a long-term perspective in the ‘new normal’. Interactions during this webinar will hopefully lead to a consensus on strengthening collective response and how universities can leverage one another in terms of the best practices and resources.  

The impact of the Coronavirus on higher learning institutions 
Given the devastation caused by COVID-19 across the world since its outbreak in China in December 2019, the impact has been felt in all spheres of the economy and global operations. Universities have also seen significant interruptions, including the UFS. Recently, RUFORUM conducted a study on the readiness of African universities to respond to COVID-19 and other natural disasters. This was meant to determine the level of preparedness of our institutions in facing this global pandemic and how to move forward as a continent while preserving the quality of the higher education that we deliver.  

The webinar will build on those findings and project a way forward in this unchartered territory of diminished financial resources, personal and academic challenges for staff, students, and institutional systems, the urgent need for improved infrastructure to respond to the demand for blended learning as well as remote learning approaches, and the limited mobility of students, academic and other staff, among others. Addressing these issues resulted in collaborations such as those initiated by RUFORUM.




News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept