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25 May 2020 | Story Prof Danie Brand | Photo iStock

We are indeed privileged to have this paper from Prof Toyin Falola to include in our celebrations of Africa Day. Toyin Falola is a world-renowned African. A scholar of African history and African studies, he holds the Jacob and Frances Sanger Mossiker Chair in the Humanities at the University of Texas, Austin. He has published, as author or editor, more than 100 scholarly books on topics ranging from diaspora, migration, empire and globalization to intellectual history, international relations, religion and culture. He has been awarded seven honorary doctorates and has received, among many other awards, the Distinguished Africanist Award from the African Studies Association, the Ibadan Foundation Award for Professional Excellence in Scholarship and the Cheikh Anta Diop Award for Excellence in African Studies. He served as Vice President of UNESCO’s International Scientific Committee, Slave Route Project from 2011 – 2015 and currently is a member of the Carnegie African Diaspora Fellows Programme and the International Committee of the Thabo Mbeki African Leadership Institute at UNISA.

In this wide-ranging paper, originally presented as keynote address at the Visions of African Unity (1930s – 2018) conference at the University of the Free State, Prof Falola begins with a tour of the intellectual history of ideas of African Continentalism (Pan-Africanism / African Unity), from Henry Sylvester Williams, through WEB du Bois, Marcus Garvey, George Padmore and Julius Nyerere, to Kwame Nkrumah. He then describes the current institutional landscape of African unity and present-day intellectual versions of African Continentalism. Asking, and answering the question ‘Why must Africa unite?’, he then proceeds, on the basis of a consideration of more contemporary intellectual versions of African continentalism such as Black Consciousness, Black Nationalism, Afropolitanism, and now Afrofuturism (which he depicts as ‘ideological dispensations of true African cultural recovery and re-orientation’), to propose a disaggregated approach to contemporary African unity that is not fixated on global-Northern models. This means that unity should (re)start small, working territorially from regional units toward a continental unit, on the one hand; and on the other, seeking unity and cooperation around discrete substantive themes, from the more obvious and traditional, such as economic policy, global politics and a reformed unified political and military system, to the less, such as common educational policy, synergizing science and technology with African culture(s) and language, culture and literary exchange.

We thank him for the gift.

News Archive

Dr Charlotte Boucher and Lindi Heyns examine possible anti-microbial activity in the skin of Western olive toad species
2014-12-22

 

Researchers Lindi Heyns and Dr Charlotte Boucher are working together on an interdisciplinary project between the Departments of Zoology and Entomology and Veterinary Biotechnology at the University of the Free State (UFS). The focus of their research is on the preliminary biochemical description of skin secretions in some South African toads.

The project forms part of an Honours study executed by Dwayne Pike under Heyns’ supervision. He is co-supervised by Dr Boucher who is assisting with the biochemical and microbiological assays.

Dr Boucher said, “Amphibians are characterised by the presence of cutaneous glands spread over the skin. There are two types of glands, namely mucous and granular (poison), located on the inner surface of the epidermis. Mucous glands are widely dispersed over the skin, while granular glands can be grouped and enlarged in specific regions. Mucous glands are generally associated with maintenance of humidity and cutaneous respiration, whereas granular glands function in chemical defence against predators and/or microbial infection. Studies indicate that the compounds produced by the granular glands belong to numerous chemical classes with diverse pharmacological activities.”

The products secreted by granular glands are rich in low molecular weight constituents of varied molecular types, including proteins, peptides and toxins. These secretions make the toad foul-tasting to predators and even toxic to other frog species. In addition, amphibians offer an attractive source of novel antimicrobials. Studies indicate that as a response to inhabiting microorganism-rich environments they synthesise and secrete a diverse array of antimicrobial peptides (AMPs) as an innate form of defence. Extensive research by various other research groups has been carried out on antimicrobial peptides of the genus Rana; however, hardly any studies have investigated the antimicrobial activity of African frog species.

The focus of this preliminary project is to determine the protein composition of the glandular secretions of the Western olive toad (Amietophrynus poweri), using biochemical tests, such as SDS-PAGE also known as protein gel electrophoresis combined with mass-spectrometry used to identify unknown peptides and proteins. This will give us an overview of the composition of the glandular secretions. Furthermore, we are also looking at microbiological tests, which include assays that test for possible anti-microbial activity against various bacterial and fungal species.

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