Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
29 October 2020 | Story Thokozane Ngcongwane | Photo Supplied
Thokozane Ngcongwane recommends that students and staff should actively seek help for their mental-health challenges.

My name is Thokozane Ngcongwane. I coordinate the UFSS1504 module in the Centre for Teaching and Learning (CTL). The journey of struggles and triumphs against mental illness has often peppered my life more than I thought. Having grown up in rural Free State, it was hard for my parents, as well as those around me, to believe that things such as mental illness exist – let alone their own son! 

I grew up with attention-deficit / hyperactivity disorder (ADHD) and was admitted numerous times as the illness was misdiagnosed and untreated. This laid the foundation for a childhood filled with amazing feats of energetic activity, but also had the downside of being misunderstood, or ill-treated due to this illness. Before I knew about this illness, I believed that because of my height (I have been given the names ‘Napoleon’ and ‘Goliath’ by various people, throughout) and stature. I was a prime target for bullying. 

Fast forward to university, and with the world as my oyster, I believed I would do well, graduate, and become the scientist I have always dreamed of becoming. Nothing could prepare me for the roller-coaster ride that, even to this day, has taught me highly valuable life lessons that I would never have received anywhere else. I started a degree in Chemistry (Extended) and was doing well in the first year. I was even fortunate enough to be selected for the F1 Leadership for Change exchange programme that took me to the USA. That was an incredible experience. Fast forward to my third year, and things took a turn for the worse. 

By 2013, I started getting panic and anxiety attacks, the origin of which was quite unknown to me at the time. I thought that I was starting to go insane and this caused a huge drop in my academics, as well as distorting my overall view on life. I started refusing to see friends and family and even shunned myself from engaging in academics. This was the start of my battles and little prepared me for the fight ahead. I took a trip outside of my surroundings and became aware of how the people I avoided cared for me, and the result was that I overcame anxiety for that period. Family, friends, and lecturers were supportive and encouraged me to do my best amid this unknown period in my life. My academics improved and I became social again. 

When I thought the worst was behind me, I was diagnosed with generalised anxiety disorder (GAD). I contacted Student Counselling and Development and received professional assistance. I started feeling better again and was on my way to graduating, albeit the journey was fraught with anxious moments. My graduation was delayed due to a credit shortfall, and this threw me in the deep end once again. This time, I dealt with it better by engaging myself in my passions – sports and the outdoors. I graduated in May 2016 and secured a temporary job as a Science teacher.

I returned home to the Qwaqwa Campus, where I became an intern in CTL. My troubles reached a boiling point in 2019, and I contacted Careways on recommendation of my head of department. It is now 2020, the year of global anxieties. I have learnt that institutions such as the South African Depression and Anxiety Group (SADAG) are available to help. Higher Health is also available to deal with issues around stigmatisation. In short, seek help and never abandon your support structures. Your mental health matters.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept