Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
17 August 2021 | Story Nonsindiso Qwabe | Photo Supplied
A story of hope, courage, resilience, and working your way to the top. Dilahlwane Mohono started working as a cleaner at the UFS in 1992. Today, she is a Senior Faculty Officer in the Faculty of Natural and Agricultural Sciences and holds two honours degrees.

Fuelled by her deep pain due to falling pregnant during her matric year, as well as the desire to one day hold a qualification, Dilahlwane Mohono – Senior Faculty Officer in the Faculty of Natural and Agricultural Sciences – says her story is her favourite, as it is a story of hope, courage, resilience, and working your way to the top.

Because of her pregnancy, Mohono did not complete Grade 12 in 1990. She got married immediately thereafter. In 1992, she began working as a cleaner for a company that was insourced to provide meals on the University of the Free State Qwaqwa Campus. She says this experience often left her with mixed feelings, as it hurt to see her peers studying further, but this is also what ultimately motivated her to complete her matric. “Graduation ceremonies were the most painful events for me. This eventually pushed me to turn to ABET to complete my matric in 1994. From there, I was determined to start my academic journey, so I registered with Stanford Business College for a Secretariat and Computer Skills Diploma. It was a six-month course, but I graduated in the end. That graduation inspired me. It motivated me to study further. Juggling work and studying became challenging, because I was a young mother and wife, but I had to attend classes after work.”

The joy of education

In 2000, she registered for a Higher Diploma with Unisa, and at the same time took up a new position in the library on campus. At the time, it was still called the University of the North Qwaqwa Campus. She recalls this as the beginning of her upward trajectory in life. “The joy of education and seeing how far I have come made me realise how much potential I have, so in 2003 I registered for a BA Sociology and English degree at the UFS, and thereafter went on to do my BA Honours in Sociology.”

She took up a new position as Assistant Officer in the Faculty of Education. Wishing to be relevant to her new faculty, Mohono completed a Postgraduate Certificate in Education (PGCE), and thereafter a second honours degree in Curriculum Studies. “I felt like I was flowing. My colleagues helped me out and I wanted to ensure that I was the best in everything, because I did not want to disappoint them. What always encouraged me, were my children. I separated from my husband in 2003, so I found myself raising my kids single-handedly, and I needed to show them that we could all make it, and life would still go on.”

In 2018, the Faculty of Natural and Agricultural Sciences advertised a senior position. Mohono says she took a chance and applied because she wanted more growth. “I am now a Senior Faculty Officer. I was privileged to be afforded an opportunity to work for the university, so I always thought – how can I work in an academic higher learning environment and not use the opportunity to study and pursue an education.”

Is there a woman who inspires you and who you would like to celebrate this Women’s Month, and why?
It has to be my late mother. She was a very hardworking woman, but she passed on very early, in her early 40s. She worked in the same dining hall I started in, and a lot of the women I worked with then worked with her too. They took me under their wings and motivated me to continue chasing my dreams. Some were not even educated themselves, but they motivated me. I drew a lot of inspiration from them.

What advice would you give to the 15-year-old you?

She must take pride in being a woman, know who she is, and know that she must be brave and confident, and run with education as the key to her success. If it wasn’t for education, I shudder to think where I could’ve been. When I look back and see what I have achieved, being able to rise from all that while single-handedly raising my children, it makes me feel very strongly about myself. I am a very powerful woman. 

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept