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11 October 2022 | Story Nonsindiso Qwabe
Qwaqwa research conference
Unpacking the role of research in society. From left: Lukhona Mnguni, Prof Pearl Sithole, Prof Dipane Hlalele, and Prof Percy Hlangothi

From socio-political dynamics and creativity in the Basotho language, to the improvement of water conditions in the upper Tugela River and antifungal studies of Cydonia oblonga extracts (known as kwepere in Sesotho) – these are just some of the highlights of the research presented at the UFS Qwaqwa Campus research conference.

With a theme focused on research as a tool for the betterment of humanity, the two-day research conference provided a space for the campus to showcase its research for sustainable development in the Afromontane region and beyond, conducted by academics and postgraduate students alike. The two-day event comprised oral student and staff presentations and sessions, with shorter presentations on the second day.

As global trends continue to challenge society to solve big and immediate problems, there has been a natural turn towards research that can make a lasting impact on local and global platforms. Through student and academic presentations, the conference provided insights into how the UFS is playing an active role in responding to some of these challenges by being outwardly focused in their approaches to problem-solving.

Balancing the sciences, industry, and society

With an intentional focus on interdisciplinarity, the guest speakers – all in different science fields – offered solutions to conducting impactful research through the lens of their own work. Prof Percy Hlangothi is currently an Associate Professor of Physical and Polymer Chemistry at Nelson Mandela University (NMU) and inaugural Director of the Centre for Rubber Science and Technology, a research entity in the Faculty of Science at the same institution. By describing his work, particularly on the production of tyres, he focused on the importance of achieving rapport between the sciences, industry, and society.

The second keynote speaker was Lukhona Mnguni, a governance, politics and development specialist and PhD candidate in Political Science at the University of KwaZulu-Natal. He currently serves as the Head of Policy and Research at the Rivonia Circle. Mnguni focused his talk on the breakthroughs of research as stemming from people, and not academic disciplines themselves. Mnguni issued a hard call towards a reflection of what the intellectual and scholarly quest for knowledge is doing to society, emphasising the need for societal involvement in issues pertaining to crises in society.

Prof Dipane Hlalele, Professor of Education at UKZN and a C2 NRF-rated researcher (2022-2027), was the final speaker for the conference. He anchored his talk on the importance of having philosophical frames behind scholarship, and spoke against approaching rural areas as lacking knowledge, to a stance of mutual understanding of knowledge schemes and models of intervention.

Campus focused on making an impact outwardly

Marking the opening of the conference, Dr Martin Mandew, Qwaqwa Campus Principal, said the campus was trying to punch above its weight and evolve its research and knowledge outputs. “We cannot just be consumers of knowledge and finished products that come from abroad. We have to produce our own knowledge that speaks to our own unique circumstances and makes complete sense of our capacities,” he said.

The conference also served as the launch platform for the campus research strategy. During the launch, Prof Pearl Sithole, Campus Vice-Principal: Academic and Research, said the strategy was centred on five frontiers. “We are trying to align what we do outwardly in terms of impact and are working on ourselves as per the commitments of the strategy. We do this excellently, because we want to advance knowledge – there is no question about that – and we put pressure on each other to do that. It does not mean that it will be easy, but we are going to engineer it such that originality and the advancement of knowledge is happening.”

The conference concluded with a prize-giving session for the best oral student presentations.

News Archive

#Women'sMonth: Save the children
2017-08-10

Description: Trudi O'Neill Tags: : rotaviruses, young children, Dr Trudi O’Neill, Department of Microbial, Biochemical and Food Biotechnology, vaccine 

Dr Trudi O’Neill, Senior lecturer in the Department of
Microbial, Biochemical and Food Biotechnology.
Photo: Anja Aucamp

Dr Trudi O’Neill, Senior lecturer in the Department of Microbial, Biochemical and Food Biotechnology, is conducting research on rotavirus vaccines.

Dr O’Neill was inspired to conduct research on this issue through her fascination with the virus. “The biology of rotaviruses, especially the genome structure and the virus’ interaction with the host, is fascinating.”

“In fact, it is estimated that, globally, ALL children will be infected with rotavirus before the age of five, irrespective of their socio-economic standing. However, infants and young children in poor countries are more vulnerable due to inadequate healthcare. The WHO estimates that approximately 215 000 deaths occur each year. This roughly equates to eight Airbus A380 planes, the largest commercial carrier with a capacity of approximately 500 seats, filled with only children under the age of five, crashing each week of every year.”

Alternative to expensive medicines 
“Currently, there are two vaccines that have been licensed for global use. However, these vaccines are expensive and poor countries, where the need is the greatest, are struggling to introduce them sustainably. It is therefore appealing to study rotaviruses, as it is scientifically challenging, but could at the same time have an impact on child health,” Dr O’Neill said.

The main focus of Dr O’Neill’s research is to develop a more affordable vaccine that can promote child vaccination in countries/areas that cannot afford the current vaccines.

All about a different approach 

When asked about the most profound finding of her research, Dr O’Neill responded: “It is not so much a finding, but rather the approach. My rotavirus research group is making use of yeast as vehicle to produce a sub-unit vaccine. These microbes are attractive, as they are relatively easy to manipulate and cheap to cultivate. Downstream production costs can therefore be reduced. The system we use was developed by my colleagues, Profs Koos Albertyn and Martie Smit, and allows for the potential use of any yeast. This enables us to screen a vast number of yeasts in order to identify the best yeast producer.”

Vaccination recently acquired a bad name in the media for its adverse side effects. As researcher, Dr O’Neill has this to say: “Vaccines save lives. By vaccinating your child, you don’t just protect your own child from a potentially deadly infection, but also other children in your community that might be too young to be vaccinated or have pre-existing health problems that prevents vaccination.” 

A future without rotavirus vaccination?

Dr O’Neill believes a future without rotavirus vaccination will be a major step backwards, as the impact of rotavirus vaccines has been profound. “Studies in Mexico and Malawi actually show a reduction in deaths. A colleague in Mozambique has commented on the empty hospital beds that amazed both clinicians and scientists only one year after the introduction of the vaccine in that country. Although many parents, mostly in developed countries, don’t have to fear dehydrating diarrhoea and potential hospitalisation of their babies due to rotavirus infection anymore, such an infection could still be a death sentence in countries that have not been able to introduce the vaccine in their national vaccination programmes,” she said. 

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