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11 July 2023 | Story André Damons | Photo Supplied
Dr Mirriam Moleko
Dr Mirriam Moleko, a lecturer in the Department of Mathematics, Natural Sciences, and Technology Education in the UFS Faculty of Education, participated in the National Research Foundation’s Black Academics Advancement Programme fellowship and got the opportunity to visit universities and schools in the USA for three weeks.

After completing the National Research Foundation’s Black Academics Advancement Programme (BAAP) fellowship, a lecturer from the University of the Free State (UFS) now wants to train more teachers on issues of access and inclusivity in different mathematics settings. She also wants to establish a centre for access and inclusivity to promote quality teaching that caters to a diverse learner population.

Dr Mirriam Moleko, a lecturer in the UFS’s Department of Mathematics, Natural Sciences, and Technology Education in the Faculty of Education, participated in the BAAP fellowship, an initiative of the National Research Foundation (NRF) and the FirstRand Foundation (FRF), from 2021 to 2022. She also got the opportunity to visit universities and schools in the USA for three weeks.

Supporting emerging academics

Dr Moleko says the BAAP is a prestigious NRF programme which supports well-structured research projects with achievable aims, sound methodologies, and demonstrated prudent use of funds. The programme supports emerging academics to ensure that they develop strong research skills, collaborate with prolific scholars in their fields, visit other universities abroad, give public lectures, and attend international conferences to establish an international footprint.

“The programme allows the candidates awarded the grant to focus on research for two years” she says. “I managed to run my teacher community research project successfully during this period. My goal as an academic and a researcher is to produce work that teachers can relate to and be able to apply in their profession. I have always aspired to empower teachers to be knowledgeable and resourceful”.

“Furthermore, my goal is to strive to partake in critical conversations that are taking place within the mathematics education field, and to contribute my skills and knowledge in addressing the existing challenges, thus being part of the solution. I believe the skills that I have gained on how to conduct quality research will assist me in achieving my goals,” she added.

Benefit from funding

During the period of her fellowship she learned about forming partnerships and collaborating with other scholars in her field, which she believes is an important skill to possess as a developing scholar.

Dr Moleko says the programme played a pivotal role in the attainment of numerous significant accomplishments in her professional career thus far. She also benefitted in terms of funding, which helped her undertake autonomous research and advanced training in her area of expertise, as well as facilitated engagement in collaborative research ventures with esteemed professionals and researchers, both domestically and abroad.

“The research leave that I got enabled me to successfully conceptualise, strategise, and implement a research endeavour that yielded a more profound comprehension of the research gap that I had identified within the teacher community, thus culminating in multiple publications in esteemed periodicals.

“The NRF-BAAP funding also enabled me to undertake training, thereby refining my skill set and augmenting my comprehension of intricate principles. The experience proved to be a crucial factor in my vocational growth and bolstered my aptitude for scholarly inquiry. It also afforded me the chance to engage in mentoring endeavours for fledgling researchers.”

Transformation of the Professoriate Mentoring Programme

Dr Moleko, who is part of the UFS Transformation of the Professoriate Mentoring Programme, says this programme is an excellent initiative which is aimed at preparing young academics for future promotions and offering them skills to be competitive. The programme’s goals include building strong academics who will follow in the footsteps of the university’s current leaders.

She says the programme is critical in supporting young academics by connecting them with seasoned mentors and scholars from various fields of study. It is essential for young academics in terms of maximising their learning, expanding their network, and gaining opportunities to help facilitate their growth.

“I see the programme as a catalyst for change necessary for the university to realise the desired results,” Dr Moleko says.

During her visit to the USA she spent two weeks at Boston College and the University of Rhode Island, and also visited the Center for Applied and Specialised Technology, the Paul V. Sherlock Center on Disabilities (Sherlock Center), and the TechACCESS Center.

“The purpose of my visit was to establish networks and collaborate with prolific scholars outside South Africa on research engagements. Furthermore, the visit was intended for me to meet with my international mentors in person regarding research engagements.

“During my research visit, Prof Elizabeth Dalton from Rhode Island University and a UDL specialist, and I focused on several academic conversations and demonstrations of Universal Design for Learning (UDL) strategies and approaches, as well as the sharing of many online resources available to support the implementation of UDL in inclusive settings.”

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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