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06 July 2023 | Story Gerda-Marié van Rooyen | Photo Supplied
Prof Ivan Turok and Prof Melanie Walker
Prof Ivan Turok and Prof Melanie Walker.

Two of the University of the Free State (UFS) SARChI Research Chairs have been included in the 2nd edition of Research.com ranking of the best scholars in the field of Social Sciences and Humanities.

Prof Melanie Walker from the UFS Higher Education and Human Development research group and SARChI Chair: Higher Education and Human Development, and Prof Ivan Turok, from the South African National Research Foundation, who hold the Research Chair in Strengthening Urban Economies: People, Place, Production and Policy, are ranked 41st (ranked 5 286 in the world) and 20th (2 825) in South Africa respectively.

According to the Research.com website, the best scientists ranking is a credible list of leading scientists from the field of Social Sciences and Humanities, established by means of a meticulous analysis of 166 880 scholars determined from multiple bibliometric data sources. For this discipline, as many as 15 317 researchers were analysed and their position in the ranking is based on a researcher’s D-index (Discipline H-index), which only includes papers and citation values for an examined discipline.

The success of a community

As a SARChI Chair in Strengthening Urban Economies: People, Place, Production, and Policy, Prof Turok explores how cities can drive economic growth and foster inclusive development in South Africa. His research analyses the factors contributing to the success of certain cities over others and identifies policies and practices that can enhance conditions for citizens and communities

He says this “pleasant surprise” (being ranked 20th in South Africa in the field of Social Sciences and Humanities) follows years of scientific work and writing.

“Research has also been a labour of love and rewarding in itself. It has fuelled my natural curiosity for learning more about the world, and I have had opportunities to visit places and meet people I would never have had otherwise,” says Prof Turok.

What it takes to be a researcher

Although one can learn the required skills and capabilities to be a good researcher, Prof Turok says having a natural yearning for knowledge and an intrinsic curiosity about the real world is helpful to have a long research career. “Careful mentoring and sound teachers are vital to become an effective researcher.”

He firmly believes research should be relevant to the society in which it is located – especially in a developing country like South Africa.

He continues by saying: “It should shed light on and help to understand the major problems and opportunities facing society, using the tools and techniques available to that particular discipline.” This honoured researcher says researchers should inform societies using simple terms and engage in discussions on matters it faces.

“Researchers should be outward-looking and interact constructively with policy-makers and practitioners to improve public policy while maintaining a healthy dose of scepticism about the intentions of the political elite and other powerful interests.”

When analysing the reasons behind varying levels of economic growth and inclusive development among cities, it is crucial to consider a diverse range of indicators. “Relying solely on a few narrow indicators can be misleading," says Prof Turok.

Indicators to take into consideration include: The economic productivity of the city (output per person) and the average income level, the level of employment in relation to the working-age population, which enables individuals to support themselves and their families financially, and the level of investment, which determines future growth, employment, and income levels.

The value of research

Prof Turok suggests that the government could play a significant role in strengthening urban economies and reducing inequalities by devolving more powers and resources to metropolitan municipalities as the effective coordination of housing and transportation investments is crucial for achieving economic growth and social inclusion in cities. He also recommends aligning the programmes and investment projects of provincial authorities and state-owned enterprises (SOEs) with those of the metropolitan areas.

“Currently, there is a disconnect between the activities of many SOEs and the interests of cities. For example, there is a considerable amount of vacant and underused land in well-located urban areas owned by SOEs, which they refuse to transfer to metros for housing purposes (highlighting the relevance of land reform in cities). Another example is the Sector Education and Training Authorities (SETAs), which operate in silos and do not align their training programmes with the needs of employers in cities,” explains Turok.

Being an internationally recognised expert in his field, Prof. Turok is regularly asked to advise esteemed organisations such as the United Nations and the African Development Bank. Prof. Turok, a former finalist for the National Science and Technology Forum (NSTF) Lifetime Achievement Award in 2021, will serve in this significant role until 2025.

Focusing on Education

Prof Walker, a distinguished scholar in the field of education sciences with an A1 rating from the National Research Foundation (NRF) – which funds SARChI – focuses on the profound impact of apartheid on education and civic life. She concentrates on (higher) education, primarily in the Global South, and addresses the intersecting research and practice challenges of decolonisation, methodology, inequalities, and justice.

This former professor of Higher Education at the University of Nottingham currently holds the esteemed position of UFS Distinguished Professor. She has supervised the production of 23 doctoral theses on higher education and human development since 2016. Additionally, she has delivered numerous keynote speeches worldwide and is an acclaimed author of books and journal articles within her area of expertise.

 


 

PHOTO

Left: Prof Ivan Turok, from the South African National Research Foundation, who holds the Research Chair in Strengthening Urban Economies: People, Place, Production and Policy, is ranked 20th (2 825) in South Africa respectively.

Right: Prof Melanie Walker, SARChI Chair: Higher Education and Human Development, is ranked 41st (ranked 5 286 in the world) in the 2nd edition of Research.com ranking of the best scholars in the field of Social Sciences and Humanities.

 


 

News Archive

Cardiology Unit involved in evaluation of drug for rare genetic disease
2013-01-04

Front from the left, are: Marinda Karsten (study coordinator and registered nurse),
Laumarie de Wet (clinical technologist), Charmaine Krahenbuhl (study coordinator and radiographer),
Lorinda de Meyer (administrator), Andonia Page (study coordinator and enrolled nurse);
back Dr Gideon Visagie (sub investigator), Dr Derick Aucamp (sub investigagtor),
Prof. Hennie Theron, (principal investigator) and Dr Wilhelm Herbst (sub investigator).
Photo: Supplied
09 January 2013


The Cardiology Research Unit at the University of the Free State (UFS) contributed largely to the evaluation of the drug Juxtapid (lomitapide), which was developed by the Aegerion pharmaceutical company and approved by the FDA (Federal Drug Administration). Together with countries such as die USA, Canada and Italy, the UFS’ Unit recruited and evaluated the most patients (5 of 29) for the study since 2008.  

The drug was evaluated in persons with so-called familial homozygous hypercholesterolemia (HoFH).  

Following its approval by the FDA, Juxtapid is now a new treatment option for patients suffering from HoFH. The drug operates in a unique way which brings about dramatic improvements in cholesterol counts.  

According to Prof. Hennie Theron, Associate Professor in the Department of Cardiology at the UFS and Head of the Cardiology Contract Research Unit, HoFH is a serious, rare genetic disease which affects the function of the receptor responsible for the removal of low-density lipoprotein cholesterol (LDL-C) (“bad” cholesterol) from the body. Damage to the LDL receptor function leads to extremely high levels of blood cholesterol. HoFH patients often develop premature and progressive atherosclerosis, which is a narrowing or blockage of the arteries.  

“HoFH is a genetically transmitted disease and the most severe form of hypercholesterolemia. Patients often need a coronary artery bypass or/and aortic valve replacement before the age of 20. Mortality is extremely high and death often occurs before the third decade of life. Existing conventional cholesterol-lowering medication is unsuccessful in achieving normal target cholesterol values in this group of patients.  

“The only modality for treatment is plasmapheresis (similar to dialysis in patients with renal failure). Even with this type of therapy the results are relatively unsatisfactory because it is very expensive and the plasmapheresis has to be performed on a regular basis.  

“The drug Juxtapid, as currently evaluated, has led to a dramatic reduction in cholesterol values and normal values were achieved in several people. No existing drug is nearly as effective.  

“The drug represents a breakthrough in the treatment of familial homozygous hypercholesterolemia. The fact that it has been approved by the FDA, gives further impetus to the findings,” says Prof. Theron.  

In future further evaluation will be performed in other forms of hypocholesterolemia.  

According to Prof. Theron, the findings of the study, as well as the recent successful FDA evaluation, once again confirms the fact that the UFS’ Cardiology Contract Research Unit is doing outstanding work.  

Since its inception in 1992, the Unit has already been involved in more than 60 multi-centre, international phase 2 and 3 drug studies. Several of these studies, including the abovementioned study, really affected the way in which cardiology functions.  

The UFS’ Cardiology Contract Research Unit is being recognised nationally and internationally for its high quality of work and is constantly approached for their involvement in new studies.  

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