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24 May 2023 | Story Dr Cornelius Hagenmeier | Photo Barend Nagel
Africa Month
Inspired by its commitment to Africa, the UFS celebrates Africa Month annually, under the motto ‘One Africa together forever'.

Click to view document#AfricaDay2023: ‘Africa is not a country, it’s a vast tapestry of innumerable stories’


A focus on the African continent is central to the University of the Free State’s (UFS) internationalisation strategy, which envisages an Africa-imbued internationalisation process that advances Africanisation and decolonisation, and includes a focus on expanding researcher networks across Africa.

The UFS considers internationalisation, Africanisation, and decolonisation as complementary processes, and prioritises engagements with the Southern African Development Community (SADC) and African countries. The university’s Vision 130 emphasises the UFS’s commitment to the development of the African continent

One Africa together forever

Inspired by its commitment to Africa, the UFS celebrates Africa Month annually, under the motto ‘One Africa together forever'. Every year the campaign focuses on a different theme – this year, it is 'Promoting and appreciating knowledge in and from Africa'. This follows 'Celebrating African Education as a Conduit for African Unity’ in 2022 and ‘Solidarity in Knowledge Production and Recording’ in 2021. The diverse contributions from members of the UFS community, including all celebrations since 2019, are available from the Africa Month section of the UFS website.

The university's internationalisation strategy commits the UFS to co-creating knowledge across the African continent. Manifold collaborations with African universities underpin this. The number of scientific publications co-authored with colleagues across Africa is growing steadily. Between 2019 and 2022, UFS researchers collaborated with 381 African institutions, which resulted in 3 002 co-authored publications.

Strengthening formal partnerships with African universities is an important aspect of the UFS focus on Africa. This presently includes the University of Botswana, the University of Namibia, the National University of Lesotho, Niger Delta University, and the University of Ibadan in Nigeria. In an opinion piece published on the 2023 UFS Africa Month website, Prof Hussein Solomon of the UFS’s Centre for Gender and Africa Studies shares that “any memorandum of understanding needs to deliver on tangible outputs” and cites the example of a collaboratively edited book which he champions together with his Niger Delta University colleague Prof Jude Cocodia.

Flags of Africa

Developing partnerships on the continent

The university invests in strengthening existing and establishing new collaborations on the African continent. In 2022, it focused on developing new partnerships in Ghana and Gabon. In Ghana, it was possible to leverage existing collaborations championed by Prof Loyiso Jita, Dean of the UFS Faculty of Education, to establish institutional collaboration with the University of the Cape Coast and formalise the relationship with the University of Ghana. In Uganda, the UFS established a new collaboration with Busitema University, which is championed by Prof Motlalepula Matsabisa from the Faculty of Health Sciences.

New partnerships were initiated with three Gabonese higher education institutions, including the International Centre for Medical Research in Franceville (CIRMF). The institution's Director-General, Prof Jean Bernard Lekana-Douki, and the Rector and Vice-Chancellor of the UFS, Prof Francis Petersen, signed a memorandum of understanding in April 2023.

Collaboration had already commenced with a visit by the CIRMF's Dr Judicaël Obame to the UFS Department of Zoology and Entomology in December 2022, during which he delivered a guest lecture and conducted a workshop on mosquito rearing. The targeted engagement with Gabon also resulted in a delegation from École de Management du Gabon University (EM-Gabon) led by its President, Prof Daniel Idiata, visiting the UFS in November 2022 and subsequently formalising its collaboration with the UFS. Together with the Masuku University of Science and Technology, also located in Gabon, PhD co-supervision commenced as a result of the new partnership.

Qwaqwa-campus-based Dr Patricks Otomo, who champions the collaboration and serves as the campus Subject Head: Zoology and Entomology, explains: “As a student in Gabon in the early 2000s, I benefited from an agreement between the Masuku University of Science and Technology, where I was an undergraduate student at the time, and Stellenbosch University. This agreement allowed me to further my studies in South Africa, eventually earning my honours, master’s, and PhD at Stellenbosch University. Knowing the benefits of such agreements and the potential for internationalisation at the UFS, two years ago I approached the Vice-Rector for Research and Internationalisation, Prof Corli Witthuhn, with the idea of intensifying the UFS collaboration with my home country, Gabon. Together with Prof Witthuhn and Dr Cornelius Hagenmeier, Director of the UFS Office for International Affairs, we visited three higher education institutions in the country. We explored collaboration with a specific focus on PhD education. The response was overwhelming: in a short period, it was possible to develop lively partnerships with all three institutions.”

One of the UFS’s important regional partners is the National University of Lesotho. Prof Petersen visited it in 2022 to strengthen the existing multi-layered collaboration, which is underpinned by a memorandum of understanding. Joint activities are taking place through the Directorate for Research Development, which coordinates the Lesotho Highlands Water Project; the Faculty of Education, the Departments of Pharmacology, Political Studies, and Africa Studies; and the Afromontane Research Unit on the UFS Qwaqwa Campus.

Flags of Africa

Connecting the UFS to African philosophy and knowledge paradigms

UFS academics are constantly at the forefront of producing and disseminating cutting-edge work on the African continent. During Africa Month, the UFS, in partnership with Sweden’s Karolinska Institutet, hosted the first Crimean-Congo haemorrhagic fever virus (CCHFV) Africa Conference, at which experts from 16 countries – including 12 African countries – deliberated on CCHFV. It was co-organised by Prof Felicity Burt, an expert in arbovirology from the UFS’s Division of Virology in the Faculty of Health Sciences.

Another example of the UFS's research leadership in Africa is that Prof Martin Nyaga, Head of the UFS Next Generation Sequencing (UFS-NGS) Unit, chairs the Africa Centre for Communicable and Preventable Diseases (Africa CDC) working group on Vaccine Preventable Diseases (VPD). Meanwhile, research collaboration in the Humanities is also flourishing. For example, Prof Chitja Twala, Vice-Dean in the Faculty of the Humanities, has a long-standing relationship with the University of Ghana’s Department of History, and travelled to the partner university in 2022 for an extended research visit.

The UFS is also engaged in many African university networks, which ensures that the university is part of contemporary African higher education discourses. For example, the UFS is an active member of the Association of African Universities (AAU), the Southern African Regional Universities Association (SARUA), and the Regional Universities Forum for Capacity Building in Agriculture (RUFORUM) .

Through its manifold African collaborations, the UFS lives up to the commitment expressed in its internationalisation strategy: to connect the UFS to African philosophy and knowledge paradigms. Moreover, the UFS’s engagements throughout Africa ensure that the university contributes significantly to promoting and appreciating knowledge in and from Africa.

UFS Rector and Vice Chancellor Prof Francis Petersen summarised this poignantly during the 2022 UFS Africa Month: “Our engagement with the world needs to ensure that the knowledge emanating from our university, our country, and our continent is shared globally.”

The UFS’s collaborations with institutions across Africa make a significant contribution in this regard.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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