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18 October 2023 | Story André Damons | Photo André Damons
Prof Mathys Labuschagne
Prof Chris Viljoen, Head of the School of Biomedical Sciences; Prof Gert van Zyl, Dean of the Faculty of Health Sciences; Prof Francis Petersen, UFS Vice-Chancellor and Principal; and Prof Mathys Labuschagne, Head of the Clinical Simulation and Skills Unit (CSSU), during the unit’s 10-year anniversary celebration.

In just 10 years, the Clinical Simulation and Skills Unit (CSSU) at the University of the Free State (UFS) went from being just a dream to becoming a national and international leader in medical simulation training.

The CSSU forms part of the School of Biomedical Sciences and was officially opened on 21 February 2013. The CSSU celebrated its 10-year anniversary on Thursday, 12 October 2023.

Prof Mathys Labuschagne, Head of the CSSU, said at the evening’s celebration that the vision and dream came true 10 years ago. “I think the requirement for the successful integration of simulation into a curriculum is first and foremost that it is based on research evidence. It is not a thumb-sucking exercise”.

“It is really seated in research and then you need passion and dedication. You cannot be successful without that, and for that I need to thank my staff – without your passion and dedication it would not be possible to excel,” said Prof Labuschagne.

Simulation important for patient safety

According to the professor, good networking is also important – between departments, professions and companies outside the university and hospital. He said simulation is important for improving patient safety and expanding the training platform.

“By doing simulation, we can train students who cannot always be accommodated on the training platform. There are also a lot of educational advantages to using simulation. Our training activities in the past 10 years grew tremendously. At the moment we have about 4000 undergraduate and postgraduate student contacts a year. Then we do a lot of certification and Continuing Professional Development (CPD) courses. During COVID-19 we did PPE training and ICU training for hospital and clinical staff in a safe environment.

“I am really proud of our research output. In the past 10 years we published 34 articles, and have another six articles currently in press. We have successfully completed eight master’s and seven PhD dissertations and there are now five students who are enrolled and all of them are simulation-associated. I cannot believe it has already been 10 years. I am very proud of the unit, and we strive for excellence in simulation education and training.”

Highlights of unit

Prof Gert van Zyl, Dean of the UFS Faculty of Health Sciences, congratulated the unit on achieving this milestone. Taking a trip down memory lane, he mentioned the names of colleagues who played a role in establishing the unit and said their contributions might not be visible in name in the unit, but they are recognised by them in achieving this milestone.

“It is an excellent achievement to have seven PhDs in 10 years. Well done. Another highlight is supporting the establishing of other simulation units at Nelson Mandela University who came to learn from us. They didn’t have to go the US. The training of staff and students during COVID-19, we had the facility. Let us not forget our simulation role at undergraduate and postgraduate training.

Cutting edge of simulation-based education and training

Prof Francis Petersen, UFS Vice-Chancellor and Principal, who gave a toast at the celebration, said the occasion is an opportunity to reflect on the excellent work done over the past decade and to consider how the unit is ideally placed to meet the aspirations that the UFS has for Vision 130 and the strategy of the university.

“The work of this unit has put the University of the Free State at the cutting edge of simulation-based education and training and the ongoing efforts of all of our staff in the unit who assist with the planning, the development, the setup, and the running of scenarios are acknowledged and greatly appreciated. I want to congratulate the leadership and the staff of the unit for the excellent work you are doing,” said Prof Petersen.

According to him, simulation education has numerous advantages such as improved patient safety, skills development, learning without involving real patients and the transfer of knowledge to the clinical environment. It creates a well-structured teaching and learning framework where simulation can be used as an educational tool assist in grasping the practical aspects of learning.

The training of specialised skills and deliberate practice are the key drivers behind clinical simulation as a training technique. It can also be applied as a tool to prepare students for a crisis situation, which requires high levels of preparedness and that is a very important aspect, said Prof Petersen.

“All these aspects of simulation-based education are something that relates very much to our vision and strategy. We want to be a research-led university, which means that it is not only doing research, but we try to focus on evidence and the research also helps us in the undergraduate programme to make it much more competitive.

“It also brings to the fore some qualities of our values, value of quality, value of impact and value of care. In addition, clinical simulation creates a vibrant learning experience for students and contributes towards our goal to meet the highest standards of excellence and impact in our teaching, learning and research.”

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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