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18 April 2024 | Story Andre Damons | Photo Charl Devenish
Dr Osayande Evbuomwan
Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine at the University of the Free State (UFS), received the first clinical PhD in nuclear medicine completed at the UFS at the April graduation ceremonies.

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans. 

News Archive

Louzanne Coetzee breaks 16-year-old world record
2016-03-24

Description: Louzanne Coetzee kampioen Tags: Louzanne Coetzee kampioen

Louzanne Coetzee (left) running the 5 000 m at the Nedbank National Championships at the Free State Athletics stadium with her guide, Khotatso Mokone (right)
Photo: Celeste Klopper Photography

Whether it’s the 5 000 m or the 1 500 m, Louzanne Coetzee is breaking records in all her races. Fans of the University of the Free State (UFS) student were elated at her triumph with the 5 000 m T11 world record at the Nedbank National Championships for the Physically Disabled on Wednesday 23 March 2016.

The record, which has stood for 16 years, was shattered by Coetzee’s stellar 19:17.06 performance. Sigita Markeviciene’s long-standing mark of 20:05.81, set at the 2000 Paralympics in Sydney, was bettered by 48.75 seconds when Coetzee and her guide, Khotatso Mokone, sprinted hand in hand past the finish line. 

Coetzee’s coach is as elated as the world-class athlete’s fans over her officially becoming the first totally blind female to clock sub-20 minute in the 5 000 m. "I am proud and grateful. She earned it through and through. She worked hard for this,” said Rufus Botha.

The experience was a surreal one for Coetzee. “It was unreal but it is exciting to be the fastest in Africa and the world. I could not have done it without the support system that I have,” she said.

"I have seldom met a student with the character and humanity of Louzanne Coetzee; she represents the best of campus and country, and is a stunning example of what we canal  achieve despite the great challenges of the present," said Prof Jonathan Jansen, Vice-Chancellor and Rector of the UFS.

New African record holder

Two days before breaking the 5 000 m world record, Coetzee set a new African record in the 1 500 m. She lowered the mark from 5:27:21 to 5:18:44, which placed her at the number nine spot in the world.

On Friday 18 March 2016 Coetzee had broken her own South African record when she ran 5 000 m in less than 20 minutes at the Free State Championships. However, the race is not an official (International Paralympic Committee) meeting, and hence remains unofficial.

What’s next?


The gold medallist is currently preparing for the Athletics Grand Prix to be held in Switzerland in May for which she is raising funds. If she is selected by SASCOC (South African Sports Confederation and Olympic Committee), her next stop is the Paralympic Games in Rio de Janeiro, which is just six months away.

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