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18 April 2024 | Story Andre Damons | Photo Charl Devenish
Dr Osayande Evbuomwan
Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine at the University of the Free State (UFS), received the first clinical PhD in nuclear medicine completed at the UFS at the April graduation ceremonies.

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans. 

News Archive

Monkey research attracts international attention
2016-07-11

Description: Monkey research attracts international attention  Tags: Monkey research attracts international attention

Prof Trudy Turner from the University of
Wisconsin-Milwaukee and Prof Paul Grobler
from the Department of Genetics at the
University of the Free State, together with one
of the students researching monkey genes.
Photo: Siobhan Canavan

For this year’s Summer School programme, Prof Paul Grobler, from the University of the Free State Department of Genetics focuses on research about the conflict between monkeys and humans in areas where monkeys are regarded as problem animals.

Global expert part of research

This year, Prof Grobler is hosting a group of students and lecturers from the United States of America (USA). The group includes Prof Trudy Turner from the University of Wisconsin-Milwaukee (UWM), a global expert on vervet monkeys. She has been working with the Department of Genetics at the UFS for the past fifteen years, and has also been appointed as an Affiliated Professor in the department.

“The Summer School programme is an opportunity for the American Primatology students to gain practical experience in Africa,” says Prof Grobler.

International interest in Summer School

This year’s Summer School programme involves four lecturers and nine students. The lecturers are from the University of Wisconsin-Milwaukee (UWM), the University of California, Los Angeles (UCLA), Boston University, and Central Washington University.

“We use the genetic information to determine
how monkeys historically infiltrated the
different areas in South Africa.”

This year’s focus is on the genetic structure of the monkeys in South Africa, and research that is being done on the differences and similarities in monkeys from different areas. “We use the genetic information to determine how monkeys historically infiltrated the different areas in South Africa,” says Prof Grobler.

Local nature reserve acting as host

The group will perform field work, including observing monkeys in the Soetdoring Nature Reserve, as well as laboratory work in the department, where they will be assisted by two laboratory technicians.

Two years ago, Prof Grobler and his department tested this idea on a smaller scale, and now they hope to make this a regular event. 

 

 

 

 

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