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18 October 2024 | Story André Damons | Photo Supplied
Prof-Maryke-Labuschagne
Prof Maryke Labuschagne is a Professor of Plant Breeding in the UFS Department of Plant Sciences.

A new research chair at the University of the Free State (UFS), led by Prof Maryke Labuschagne, a Professor of Plant Breeding in the UFS Department of Plant Sciences, hopes to increase food and nutritional security in South Africa through crops that have intrinsic high nutritional value.

The Breeding Climate-Resilient Vegetables and Grains research chair was established in partnership with the Agricultural Research Council (ARC) and the Department of Agriculture, Land Reform and Rural Development (DALRRD). It will be hosted within the Faculty of Natural and Agricultural Sciences (NAS) alongside the other ARC-DALLRD-UFS research chairs, namely Climate Change and Agriculture, Innovative Agro-processing for Climate-smart Food System, Agriculture Risk Financing and Sustainable Livestock Production. 

The aim of the new ARC-DALLRD-UFS research chair, explains Prof Labuschagne, who is also leading the National Research Foundation (NRF) SARChI Chair in Diseases and Quality of Field Crops, is to breed climate resilient crops with high levels of nutrients such as iron, zinc, provitamin A and essential amino acids, as well as disease resistance, in collaboration with the ARC.

Breeding of climate resilient crops

“We are all aware of the need for food security in South Africa. Climate change is already negatively impacting food production. With this research chair, in collaboration with the ARC, we hope to increase food security through crops that have intrinsic high nutritional value, for example, high levels of iron and zinc and provitamin A, of which there are high levels of deficiency in our population, and at the same time increase climate resilience (such as heat and drought tolerance) in these crops.

“We will be working on breeding climate-resilient, nutrient-rich and disease-resistant pigeon pea and cowpea cultivars; maize rich in provitamin A, iron and zinc; highly nutritious sweet and bitter sorghum; rust-resistant and good-quality wheat; high-yielding and nutritious indigenous vegetables such as amaranth and amadumbi; and research on potato, sweet potato and cassava for human and industrial uses,” says Prof Labuschagne.

The new chair will complement the research that is already being done for the SARChI chair, but with the ARC as partner. It will combine the expertise and resources of Plant Breeding at the UFS with that of the ARC-VIMP (Vegetable, Industrial and Medicinal Plants), ARC-GC (Grain Crops) and ARC-SC (Small Grains). The chair research will include orphan crops such as cowpea, pigeon pea and indigenous vegetables, as well as root and tuber crops such as potato and cassava, and cereals such as wheat, maize and sorghum.

Collaborative research

“The focus of this chair is on collaborative research and student training with the ARC, but the research area will still focus on the development of nutrient-rich and disease-resistant food-security crops. It will also have an additional focus of climate resilience, and the inclusion of orphan crops indigenous to Africa and South Africa.”

Prof Labuschagne says it is exciting that collaborative research can now be done with the unique expertise and resources (laboratory equipment, fields, greenhouses etc.) of several research institutes for the benefit of food and nutritional security in South Africa. Doing this research in a large team with lots of expertise in different areas will certainly yield more and better results with a larger impact on food security.

“This is a very exciting development in agricultural research now that we are part of a large team all working towards the same goal of improving food security, sharing expertise and resources and also doing collaborative training of MSc and PhD students who will become the scientists of tomorrow, taking this quest into the future.”

Prof Vasu Reddy, Deputy Vice-Chancellor: Research and Internationalisation, says this chair is aligned to the UFS Vision 130 strategy, shaped by excellence and impact, sustainability and society. “This distinguished chair led by Prof Labuschagne recognises exceptional achievement and pre-eminence in the field to catalyse and ignite new talent and new knowledge. It marks an exciting opportunity to deepen our understanding of breeding climate-resilient vegetables and grains aligned to our expertise in agriculture.”

News Archive

#Women'sMonth: Save the children
2017-08-10

Description: Trudi O'Neill Tags: : rotaviruses, young children, Dr Trudi O’Neill, Department of Microbial, Biochemical and Food Biotechnology, vaccine 

Dr Trudi O’Neill, Senior lecturer in the Department of
Microbial, Biochemical and Food Biotechnology.
Photo: Anja Aucamp

Dr Trudi O’Neill, Senior lecturer in the Department of Microbial, Biochemical and Food Biotechnology, is conducting research on rotavirus vaccines.

Dr O’Neill was inspired to conduct research on this issue through her fascination with the virus. “The biology of rotaviruses, especially the genome structure and the virus’ interaction with the host, is fascinating.”

“In fact, it is estimated that, globally, ALL children will be infected with rotavirus before the age of five, irrespective of their socio-economic standing. However, infants and young children in poor countries are more vulnerable due to inadequate healthcare. The WHO estimates that approximately 215 000 deaths occur each year. This roughly equates to eight Airbus A380 planes, the largest commercial carrier with a capacity of approximately 500 seats, filled with only children under the age of five, crashing each week of every year.”

Alternative to expensive medicines 
“Currently, there are two vaccines that have been licensed for global use. However, these vaccines are expensive and poor countries, where the need is the greatest, are struggling to introduce them sustainably. It is therefore appealing to study rotaviruses, as it is scientifically challenging, but could at the same time have an impact on child health,” Dr O’Neill said.

The main focus of Dr O’Neill’s research is to develop a more affordable vaccine that can promote child vaccination in countries/areas that cannot afford the current vaccines.

All about a different approach 

When asked about the most profound finding of her research, Dr O’Neill responded: “It is not so much a finding, but rather the approach. My rotavirus research group is making use of yeast as vehicle to produce a sub-unit vaccine. These microbes are attractive, as they are relatively easy to manipulate and cheap to cultivate. Downstream production costs can therefore be reduced. The system we use was developed by my colleagues, Profs Koos Albertyn and Martie Smit, and allows for the potential use of any yeast. This enables us to screen a vast number of yeasts in order to identify the best yeast producer.”

Vaccination recently acquired a bad name in the media for its adverse side effects. As researcher, Dr O’Neill has this to say: “Vaccines save lives. By vaccinating your child, you don’t just protect your own child from a potentially deadly infection, but also other children in your community that might be too young to be vaccinated or have pre-existing health problems that prevents vaccination.” 

A future without rotavirus vaccination?

Dr O’Neill believes a future without rotavirus vaccination will be a major step backwards, as the impact of rotavirus vaccines has been profound. “Studies in Mexico and Malawi actually show a reduction in deaths. A colleague in Mozambique has commented on the empty hospital beds that amazed both clinicians and scientists only one year after the introduction of the vaccine in that country. Although many parents, mostly in developed countries, don’t have to fear dehydrating diarrhoea and potential hospitalisation of their babies due to rotavirus infection anymore, such an infection could still be a death sentence in countries that have not been able to introduce the vaccine in their national vaccination programmes,” she said. 

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