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16 September 2024 | Story André Damons | Photo Supplied
Dr Mampoi Jonas and Prof Jan Du Plessis
Dr Mampoi Jonas, senior lecturer in Paediatric Oncology and Prof Jan Du Plessis, Head of the Paediatric Oncology Unit at the University of the Free State (UFS).

A campaign like Childhood Cancer Awareness Month is vital in creating awareness and educating people about the early signs and symptoms of certain cancers. This can significantly improve the survival rate of young patients. More than 50% of people diagnosed with cancer live for more than five years, and some types of cancer have survival rates as high as 90%.

This is according to Prof Jan Du Plessis, Head of the Paediatric Oncology Unit, and Dr Mampoi Jonas, senior lecturer in Paediatric Oncology, at the University of the Free State (UFS).

“Early diagnosis is crucial because early-stage cancer is more responsive to treatment and less likely to be fatal. Due to the rarity of childhood cancer, many children get misdiagnosed or diagnosed too late with advanced stage disease. The delayed detection and diagnosis diminish the chances of successful treatment.

“Cancer awareness educates families, communities, primary-care nurses and doctors about the early signs and symptoms of certain cancers. When people are aware of these, they are more likely to be on the lookout for them when children present with suspicious clinical symptoms and signs. This also gives parents the confidence to seek help early and even make people better able to support those with the disease once a diagnosis is made,” say the paediatric oncologists.

Recorded incidences on the rise

Though childhood cancer is rare, representing only 1.2% of all cancers worldwide, the recorded incidences are increasing. In the US cancer is the number one cause of death among children, while more than 100 000 children worldwide die because of cancer.

Prof Du Plessis says there are more than 12 major types of childhood cancers and multiple subtypes. The most common types are leukaemia, lymphoma (tumours that begin in the lymph glands), brain tumours, nephroblastoma (cancer of the kidneys) and soft tissue sarcomas. Most cancers in children are thought to develop as a result of mutations in genes that lead to uncontrolled cell growth and eventually cancer.

According to Dr Jonas, most cancers in children are thought to develop because of mutations in genes that lead to uncontrolled cell growth and eventually cancer. Although environmental pollutants have been implicated in some cancers, our experience has been that most paediatric cancers rather occur sporadically.

The reasons for the increase of reported incidence of cancer in children, could be to the increase in population numbers and better awareness of childhood cancers. Another reason might be that more children are being diagnosed who were previously misdiagnosed, explains Prof Du Plessis.

Treatments

Childhood cancers are treated with chemotherapy, surgery and radiation therapy under the care of a paediatric oncologist. Not much can be done about the genetic mutations, but parents can ensure that their children stay safe in the sun (slip, slop, slap campaign – slip on a shirt, slop on some suncream and slap on a hat), get their children vaccinated against HPV infection, help their children stay active and keep a healthy weight and talk to them about smoking.

Prof Du Plessis says the South African paediatric oncology community are currently busy with a few research studies regarding standardising treatment protocols for certain childhood cancers. This is to find out how our children are responding to these protocols and to see if there are different factors affecting the outcomes of South African children. These protocols are based on international treatment protocols with a few adjustments for local circumstances and resources.

They are involved with the Hodgkins lymphoma, neuroblastoma, retinoblastoma, germ cell tumour studies and contributed to a research study evaluating the nutritional status and interventions to improve the nutritional status of local patients. Registrars presented local (Bloemfontein) data at an international conference (SIOP Africa) on hepatoblastomas and osteosarcomas.

“For many childhood cancer may not be a priority or something they would like to think about. Unfortunately for many of my patient’s parents the truth is that the day before their children were diagnosed with cancer, they were also not a cancer parent. However, their lives changed for ever with these four words: ‘Your child has cancer’.

“Childhood cancer is more than chemo and no hair. It is rather about resilience, strength, hope, family, courage, cuddles, and bravery. Your life will be changed for ever if you have ever seen a child fight cancer. Their smiles will make your heart melt and make you realise the importance of the simple things in life,” declare Prof Du Plessis and Dr Jonas.

Early warning signs for parents

The Childhood Cancer Foundation South Africa (CHOC) has a campaign which emphasises the importance of recognising the early warning signs of childhood cancer. They use Siluan’s Early Warning Signs to raise awareness and promote early diagnosis which are:

• S – Seek medical help early for ongoing symptoms
• I – White spot in the eye, new squint, sudden blindness or bulging eyeball.
• L – Lump on the stomach, pelvis, head, arms, legs, testicle, or glands
• U – Unexplained fever present for over two weeks, weight loss, fatigue, pale appearance, easy bruising, and bleeding
• A – Aching bones, joints, back, and easy fractures

• N – Neurological signs, a change in walk, balance or speech, regression, continuous headaches with/without vomiting, and an enlarged head

While these symptoms can be subtle or easily attributed to other causes, it’s important to consult a doctor if they persist or worsen. If you notice any of these symptoms in a child or teen, seek professional medical help promptly. Early detection of cancer saves lives in both children and teens.

News Archive

Year-long programme to celebrate the story of life and survival
2009-02-13

 
At the launch of the UFS's year-long programme to celebrate the story of life and survival were, from the left: Prof. Schalk Louw, Department of Zoology and Entomology, Prof. Jo van As, Department of Zoology and Entomology, Prof. Maitland Seaman, Centre for Environmental Management, and Prof. Matie Hoffman, Department of Physics. All four are associated with the UFS.
Photo: Hannes Pieterse

A year-long programme to celebrate the 200th anniversary of the birth of Charles Darwin and the 150th anniversary of the publication of his scientifically important book “The Origin of Species” was launched yesterday (the birth date of Darwin) by the University of the Free State (UFS) on its Main Campus in Bloemfontein.

The UFS is the only university in the country that is presenting such an extensive programme on life and survival. Yesterday’s launch programme entailed a portrayal of the life of Darwin and a presentation on what nature tells us about cosmic history. It was the start of a year-long lecture programme in which various departments at the UFS will take part.

“The lecture programme, called “The story of life and survival”, forms a cycle of the progress of man and does not only focus on Darwin. The programme aims to portray the influence of Darwin’s theory of evolution on a wide range of disciplines. We see this as a good opportunity to promote science in its broadest context,” says Prof. Jo Van As, head of the Department of Zoology and Entomology at the UFS.

The lecture programme will include topics such as the geological evolution of our planet, extinction, Darwinian agriculture, the road to civilisation, the proliferation of technology and communication, human demography and the human impact on the environment. It will be concluded in February 2010 with a lecture on the future of evolution.

The programme is spearheaded by the Department of Zoology and Entomology at the UFS, in conjunction with the National Museum and the Central University of Technology.

“Today evolution is no longer considered to be a theory and is widely accepted by most serious scientists as the process responsible for the diversity of life on our planet,” says Prof. Van As.

Complete programme:

26 February 2009: The geological evolution of our planet
13 March 2009: Origin of life, prokaryotes and eukaryotes
24 March 2009: Extinction
16 April 2009: Evolution and biodiversity of plants
30 April 2009: Evolution and biodiversity of animals
14 May 2009: The mechanisms of evolution: Heredity and Natural Selection
28 May 2009: Origin of humankind
4 June 2009: Darwinian agriculture
30 July 2009: Road to civilisation
6 August 2009: Human demography
20 August 2009: Proliferation of technology and communication
10 September 2009: Human impact: On the environment
8 October 2009: Human impact: Resistance, ectoparasites, HIV/Aids, antibiotics
22 October 2009: How to care for the world
12 February 2009: The future of evolution

Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za
13 February 2009

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