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10 November 2025 | Story Precious Shamase | Photo Supplied
Zandile Mncube
Dr Zandile Mncube presenting her research at the International Mountain Conference (IMC2025) at the University of Innsbruck, Austria.

In a remarkable milestone for both her academic and personal journey, Dr Zandile Mncube, a 27-year-old newly conferred PhD graduate from the University of the Free State (UFS), recently presented her research at the prestigious International Mountain Conference (IMC2025), hosted by the University of Innsbruck, Austria. The event marked not only her debut on the global research stage but also her first international trip and first flight – an experience she described as transformative. 

 

A mountain of research: From UFS weather stations to the global stage

Dr Mncube's journey to this international platform began with encouragement from Prof Ralph Clark, Director of the Afromontane Research Unit, and Dr Melissa Hansen, Lecturer in the Department of Geography, who recognised her potential and urged her to submit an abstract to the conference. 

"Prof Clark proposed that I write an abstract for this conference," Dr Mncube explained. “I had been managing the UFS weather stations and had just begun using their data, so I based my abstract on that work.” 

Her submission was accepted, earning her the opportunity to showcase her research alongside an impressive array of global scholars. The IMC2025, held biennially, brings together experts from across the world to discuss diverse aspects of mountain studies. Dr Mncube formed part of a strong South African delegation that included two students from UFS and one from the University of Cape Town (UCT).

"It was inspiring to see how diverse and multidisciplinary the field is," she said. "It was good to see that, as South Africans, we do fit into the global research stage and can hold our own through the quality of our work.”  

 

Vision for the future: expanding research horizons 

Having been part of the UFS community since 2017 - serving in various roles from student assistant to her current practical and research position – Dr Mncube is now looking ahead to further her research career.

"I want to explore more on the research side of things," she shared. “While I’ve gained valuable experience that could lead to lecturing, my immediate goal is to deepen my involvement in research and fieldwork within Geography.”   

 

A transformative experience and a call for greater support

Describing her participation at the IMC as a "transformative experience, both professionally and personally," Dr Mncube reflected on how it broadened her understanding of global scientific collaboration and highlighted the vital contribution of African researchers. 

She noted there remain "notable gaps in data and contextual understanding that African researchers are uniquely positioned to address," particularly in underrepresented mountain regions.

Dr Mncube strongly advocates for more South African students to be supported in attending international conferences. She observed that several of her peers at the IMC had earned recognition through the Southern African Mountain Conference 2025 (SAMC), further illustrating the value of regional and international engagement. 

"If more students are supported to attend conferences like IMC, it could open doors for them to engage in global research and collaborations that extend far beyond our borders," she said. 

Expressing her heartfelt appreciation, she concluded by thanking Prof Clark and Dr Hansen for their guidance and support, which made her international debut possible.

News Archive

UFS cardiac team leading with project
2017-05-31

 Description: Cardiac team read more Tags: Cardiac team read more

Prof Peter Schultheiss of the Charité University in Berlin,
Germany, visited the Robert WM Frater Centre for
Cardiovascular Research at the UFS for a study regarding
cardiomyopathy, a significant cause of fatal heart failure
among Africans. From the left are Dr Glen Taylor,
Dr Danie Buys, Prof Makoali Makatoko,
Prof Schultheiss and Prof Francis Smit.
Photo: Rulanzen Martin

A team of cardiac doctors associated with the Robert WM Frater Cardiovascular Research Centre at the University of the Free State’s (UFS) Faculty of Health Sciences has commenced with a pioneering research project regarding idiopathic dilating cardiomyopathy.  

An Afrocentric research focus
Prof Francis Smit, Head of the Department of Cardiothoracic Surgery at the UFS and Head of the Frater Centre, describes dilating cardiomyopathy as a heart muscle disease that is quite common, particularly among people of African descent. The disease weakens the heart muscle, which in turn leads to heart failure.

“To date there is no curable treatment for this condition and 50% of patients that have shown heart failure, died within a period of five years. The causes of this condition have been unknown in the majority of patients. But over the past few years major strides have been made where virus infections of the heart muscle or myocarditis have been identified as a possible underlying cause. Various genetic diseases are also linked to it,” says Prof Smit.

International collaborations ensure success
According to Prof Smit, the project is being run in conjunction with Prof Heinz-Peter Schultheiss of the Charité University and the Institute for Cardiac Diagnostics and Therapy in Berlin, Germany.

“We have been working on the project over the past 18 months and I have twice visited Prof Schultheiss in Germany. He is now visiting us in Bloemfontein. We have established a collaborative project focused on patients in central South Africa”.
Prof Schultheiss is a world leader regarding the diagnosis, pathology and treatment of dilating cardiomyopathy, says Prof Smit.

“He brings a lifetime of research experience to Bloemfontein and is internationally renowned as the father of myocardial or heart muscle biopsies.

“His pioneering work on the discipline has led to diagnostic accuracy that has induced purposeful and personalised treatment of dilating cardiomyopathy and has brought about dramatic changes in some subsets of patients’ life expectancy and their cure.”

Solving problems close to home
According to Prof Mokoali Makatoko, Head of the Department of Cardiology, there are more than 1500 new cases of heart failure identified annually at the Universitas Academic Hospital, of which approximately 30% are attributed to cardiomyopathy. “With the use of endomyocardial biopsies the team hopes to treat viruses unique to Southern Africa as well as other underlying causes of dilating cardiomyopathy.”

Prof Stephen Brown, Head of Paediatric Cardiology at the Universitas Academic Hospital, says children suffering from this disease never reach a mature age and those under his supervision will also be undergoing these tests. Various other departments at the UFS will also participate in this project. Profs Makatoko and Brown did the first four endomyocardial biopsies under the management of Prof Schultheiss during the past week. The results will be available in the coming weeks after which the project will be officially launched and patient recruitment will start in earnest.

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