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UFS researcher Zandile Mncube reaches new heights at International Mountain Conference in Austria

10 November 2025 | Story Precious Shamase | Photo Supplied

In a remarkable milestone for both her academic and personal journey, Dr Zandile Mncube, a 27-year-old newly conferred PhD graduate from the University of the Free State (UFS), recently presented her research at the prestigious International Mountain Conference (IMC2025), hosted by the University of Innsbruck, Austria. The event marked not only her debut on the global research stage but also her first international trip and first flight – an experience she described as transformative.

A mountain of research: From UFS weather stations to the global stage

Dr Mncube's journey to this international platform began with encouragement from Prof Ralph Clark, Director of the Afromontane Research Unit, and Dr Melissa Hansen, Lecturer in the Department of Geography, who recognised her potential and urged her to submit an abstract to the conference.

"Prof Clark proposed that I write an abstract for this conference," Dr Mncube explained. “I had been managing the UFS weather stations and had just begun using their data, so I based my abstract on that work.”

Her submission was accepted, earning her the opportunity to showcase her research alongside an impressive array of global scholars. The IMC2025, held biennially, brings together experts from across the world to discuss diverse aspects of mountain studies. Dr Mncube formed part of a strong South African delegation that included two students from UFS and one from the University of Cape Town (UCT).

"It was inspiring to see how diverse and multidisciplinary the field is," she said. "It was good to see that, as South Africans, we do fit into the global research stage and can hold our own through the quality of our work.”

Vision for the future: expanding research horizons

Having been part of the UFS community since 2017 - serving in various roles from student assistant to her current practical and research position – Dr Mncube is now looking ahead to further her research career.

"I want to explore more on the research side of things," she shared. “While I’ve gained valuable experience that could lead to lecturing, my immediate goal is to deepen my involvement in research and fieldwork within Geography.”

A transformative experience and a call for greater support

Describing her participation at the IMC as a "transformative experience, both professionally and personally," Dr Mncube reflected on how it broadened her understanding of global scientific collaboration and highlighted the vital contribution of African researchers.

She noted there remain "notable gaps in data and contextual understanding that African researchers are uniquely positioned to address," particularly in underrepresented mountain regions.

Dr Mncube strongly advocates for more South African students to be supported in attending international conferences. She observed that several of her peers at the IMC had earned recognition through the Southern African Mountain Conference 2025 (SAMC), further illustrating the value of regional and international engagement.

"If more students are supported to attend conferences like IMC, it could open doors for them to engage in global research and collaborations that extend far beyond our borders," she said.

Expressing her heartfelt appreciation, she concluded by thanking Prof Clark and Dr Hansen for their guidance and support, which made her international debut possible.

News Archive

Nanotechnology breakthrough at UFS

2010-08-19

Ph.D students, Chantel Swart and Ntsoaki Leeuw

Scientists at the University of the Free State (UFS) made an important breakthrough in the use of nanotechnology in medical and biological research. The UFS team’s research has been accepted for publication by the internationally accredited Canadian Journal of Microbiology.

The UFS study dissected yeast cells exposed to over-used cooking oil by peeling microscopically thin layers off the yeast cells through the use of nanotechnology.

The yeast cells were enlarged thousands of times to study what was going on inside the cells, whilst at the same time establishing the chemical elements the cells are composed of. This was done by making microscopically small surgical incisions into the cell walls.

This groundbreaking research opens up a host of new uses for nanotechnology, as it was the first study ever in which biological cells were surgically manipulated and at the same time elemental analysis performed through nanotechnology. According to Prof. Lodewyk Kock, head of the Division Lipid Biotechnology at the UFS, the study has far reaching implications for biological and medical research.

The research was the result of collaboration between the Department of Microbial, Biochemical and Food Biotechnology, the Department of Physics (under the leadership of Prof. Hendrik Swart) and the Centre for Microscopy (under the leadership of Prof.Pieter van Wyk).

Two Ph.D. students, Chantel Swart and Ntsoaki Leeuw, overseen by professors Kock and Van Wyk, managed to successfully prepare yeast that was exposed to over-used cooking oil (used for deep frying of food) for this first ever method of nanotechnological research.

According to Prof. Kock, a single yeast cell is approximately 5 micrometres long. “A micrometre is one millionth of a metre – in laymen’s terms, even less than the diameter of a single hair – and completely invisible to the human eye.”

Through the use of nanotechnology, the chemical composition of the surface of the yeast cells could be established by making a surgical incision into the surface. The cells could be peeled off in layers of approximately three (3) nanometres at a time to establish the effect of the oil on the yeast cell’s composition. A nanometre is one thousandth of a micrometre.

Each cell was enlarged by between 40 000 and 50 000 times. This was done by using the Department of Physics’ PHI700 Scanning Auger Nanoprobe linked to a Scanning Electron Microscope and Argon-etching. Under the guidance of Prof. Swart, Mss. Swart en Leeuw could dissect the surfaces of yeast cells exposed to over-used cooking oil.

The study noted wart like outgrowths - some only a few nanometres in diameter – on the cell surfaces. Research concluded that these outgrowths were caused by the oil. The exposure to the oil also drastically hampered the growth of the yeast cells. (See figure 1)

Researchers worldwide have warned about the over-usage of cooking oil for deep frying of food, as it can be linked to the cause of diseases like cancer. The over-usage of cooking oil in the preparation of food is therefore strictly regulated by laws worldwide.

The UFS-research doesn’t only show that over-used cooking oil is harmful to micro-organisms like yeast, but also suggests how nanotechnology can be used in biological and medical research on, amongst others, cancer cells.

Figure 1. Yeast cells exposed to over-used cooking oil. Wart like protuberances/ outgrowths (WP) is clearly visible on the surfaces of the elongated yeast cells. With the use of nanotechnology, it is possible to peel off the warts – some with a diameter of only a few nanometres – in layers only a few nanometres thick. At the same time, the 3D-structure of the warts as well as its chemical composition can be established.

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za
18 August 2010

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