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09 December 2022 | Story Leonie Bolleurs | Photo Leonie Bolleurs
Dr Refilwe Mogale
Dr Refilwe Mogale received her PhD in Chemistry. She is fascinated by the ability of chemistry and science in general to solve some of the world’s most pressing issues, such as water scarcity.

“Chemistry chose me,” says Dr Refilwe Mogale, who wanted to enrol for Psychology years ago when she decided to study at the University of the Free State (UFS). 

“On the day of registration, however, as I was standing in the queue, something inside me said this was not the right choice for me. Ultimately, I chose my second option, which was a BSc degree majoring in biology, physics, and chemistry.”

“Once I started the BSc programme, I gravitated towards chemistry, and as difficult as it was juggling classes and six-hour practical sessions, I loved it. I am fascinated by the ability of chemistry and science in general to solve some of the world’s most pressing issues, such as water scarcity, alternative generation, access to antibacterial hygiene products, as well as novel strategies to cure diseases, among many other things.”

The UFS awarded Dr Mogale a PhD in Chemistry on 9 December 2022.

Addressing a global challenge

Being passionate about applied chemistry – where scientific research can be used to create products to address everyday problems – Dr Mogale focused her thesis on Aluminium- and Zirconium-based metal organic frameworks with azobenzene and stilbene dicarboxylate ligands for use in wastewater treatment. 

She has also published multiple articles on topics of environmental chemistry and wastewater management in international journals. 

Dr Mogale is of the opinion that water pollution by financially lucrative industries and access to clean drinkable water is one of our planet’s most challenging environmental and health issues. “The waste generated by some of the industries that contribute heavily to our country’s economy, such as the textile, agricultural, and medical industries, may end up in the limited drinking water resources we have. I chose my research topic because I wanted to positively contribute to this global challenge,” she says.

“My research was based on making highly porous metal-organic frameworks (MOF) to be used in the wastewater treatment technique called adsorption,” explains Dr Mogale, describing MOFs as “really cool three-dimensional ‘sponges’ that can suck up very high amounts of gases and pollutants, trapping them in their pores. These trapped materials can later be released from the pores to be re-used when MOFs are exposed to certain stimuli.”

She continues, “Low cost and simplicity make this method attractive for industrial use. Considering our current energy crisis, other methods are not ideal, since they require large amounts of energy.” 

Focused on developing highly effective adsorbent for wastewater purification systems, Dr Mogale synthesised a novel MOF with one of the highest adsorption capacities compared to existing counterparts.

According to her, should MOFs with their incredibly high surface areas – which allow them to absorb more waste than their existing counterparts – be implemented in wastewater purification systems, they would be able to address the environmental issue of water pollution and the health issue of access to drinkable water.

Tackling everyday societal issues

She is currently doing a postdoctoral fellowship in the UFS Department of Chemistry – to broaden her knowledge in chemistry beyond MOFs. Her plans are, however, to transition to industry and ultimately entrepreneurship, where she will be able to develop scientific products that can tackle everyday societal issues. 

Dr Mogale dreams of adding value to society by practically contributing to the water crisis issue through the development of low-cost water generation and purification products.

News Archive

Prestige Scholar hosts Prof John Helliwell of Manchester University
2015-12-08

From left is Prof John R. Helliwell (School of Chemistry, University of Manchester), Dr Madeleine Helliwell (School of Chemistry, University of Manchester), Prof Andre Roodt (Department of Chemistry, University of the Free State) and Dr Alice Brink (Department of Chemistry, University of the Free State).
Photo: Steven Collett

At the invitation of Dr Alice Brink of the Department of Chemistry, Prof John Helliwell, the 2015 Max Perutz Prize winner, and his wife, Dr Madeleine Helliwell, visited the University of the Free State (UFS).
The Helliwells, both chemists of note, took part in a series of lectures and exchanges on the Bloemfontein and Qwaqwa Campuses.
This visit from 9-19 November 2015 was the consequence of Dr Brink’s participation in the Vice-Chancellor’s Prestige Scholars Programme (PSP) initiative to encourage the broadening of the international footprint of the next generation of scholars in the academy.

Two year collaboration

Dr Brink and Prof Helliwell from Manchester University have a standing collaboration going back two years. Dr Brink, an NRF Thuthuka grant holder and a member of the PSP since 2013, has spent almost eight months in Manchester, collaborating with Prof Helliwell on her study of the successful interaction of rhenium tricarbonyl complexes with proteins determined via protein crystallography.
Their collaboration resulted from the close association of Prof Helliwell and Prof Andre Roodt from the UFS Department of Chemistry, both former presidents of the European Crystallographic Association.

Sharing academic expertise

Prof Helliwell, the 2014 American Crystallographic Association Patterson Award winner for his “pioneering contributions to the global development of the instrumentation, methods and applications of synchrotron radiation in macromolecular crystallography”, gave three lectures in the Department of Chemistry, two on the Boemfontein Campus, and the other on the Qwaqwa Campus on 13 November 2015.

Dr Helliwell, former co-editor of the Acta Crystallographica Section C: Crystal Structure Communications journal, consulted with postgraduate students from the Departments of Chemistry and Biochemistry.

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