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29 July 2022 | Story André Damons | Photo André Damons
UFS Traditional Medicine
Recardia Schoeman, Scientific Officer in the Department of Pharmacology, gave Prof Paul Waako, Dr Samuel Baker Obakiro, and Dr Richard Oriko Owor from the Busitema University a tour of the department and its laboratories.

Prof Motlalepula Matsabisa, Director of Pharmacology at the University of the Free State (UFS), played host to academics from the Busitema University in Uganda for benchmarking on traditional medicine and to establish collaboration between the two institutions.

Prof Paul Waako, Vice-Chancellor of the Busitema University – who was part of the visiting party – and Prof Francis Petersen, UFS Rector and Vice-Chancellor, signed a collaboration agreement that enables the two institutions to work together and to get involved in the exchange of expertise as part of the collaboration.

Dr Samuel Baker Obakiro, Lecturer of Pharmacology and Therapeutics and Head of the Department of Pharmacology, and Dr Richard  Oriko Owor, a natural products chemist, accompanied Prof Waako on the visit to the UFS from 18 to 21 July, during which they undertook tours of various departments and laboratories, including Pharmacology, Virology, Chemistry, Genetics, Physics, Microbiology, and others. They also visited FARMOVS.

 

Establishing collaboration

Uganda – through their Ministry of Science, Technology, and Innovation – has a national drive to ensure that science contributes to socio-economic development through their major national agenda, which promotes local production, reduces importation, and increases exportation of goods. Dr Monica Musenero Masanza, Minister of Science, Technology, and Innovation, wants to ensure that the capacity of Ugandan scientists to conduct applied research will promote national development and reduce poverty.

Prof Waako said they came to the UFS to establish collaboration, as universities have an obligation to ensure that science improves the socio-economic situation in Africa. They would like to work with the UFS to ensure that science strengthens science in order to serve the people.

“Currently, one of the biggest challenges is the local manufacturing of pharmaceuticals, and that is why we came to the Department of Pharmacology. We need to come together as African universities and use all the existing capacities to transform the lives of our people.”

“African traditional medicine has a lot to offer, and a lot of research has been done, but we have not been able to take it to the level of final commercialisable products. This is the reason of us coming here, we want to create that link to ensure that the science – which has already been identified and established – is able to move to product production,” says Prof Waako.

 

At the right place

They decided to visit the UFS after meeting Prof Matsabisa during his visit to their country’s universities as part of the WHO team.

According to Dr Obakiro, when walking down the corridors of the department, they can see that they are in the right place. “We are also looking at mentorship, as our university is still very young. I am happy and privileged to be here. We cannot succeed on our journey if we do not stand on your shoulders.”

Dr Obakiro said they are also looking at how to set up partnerships between academia and industry, as well as collaboration between the different academic departments, such as pharmacology, chemistry, microbiology, and virology, and how these collaborative initiatives can be effective and efficient to drive their agenda.

In welcoming the colleagues from West Africa, Prof Matsabisa said, “Let’s find a way to crawl together and eventually run together. If you want to move into drug discovery and development, no single scientist can do it alone, it is a multidisciplinary approach. It is a team effort with a shared vision. We have some experience that we can share with you, but we are not perfect, and I think we can learn together.”

News Archive

Newly operational sequencing unit in genomics at UFS
2016-09-09

Description: Next Generation Sequencing  Tags: Next Generation Sequencing

Dr Martin Nyaga and his research assistant,
Tshidiso Mogotsi in the Next Generation
Sequencing Laboratory.
Photo: Charl Devenish

The Next Generation Sequencing (NGS) unit at the UFS was established as an interdisciplinary facility under the Directorate for Research Development, Faculty of Health Sciences and Faculty of Natural and Agricultural Sciences.

The aim of the NGS facility is to aid internal and external investigators undertaking studies on Deoxyribonucleic acid (DNA) sequencing, assembly and bioinformatics approaches using the more advanced Illumina MiSeq NGS platform.

The NGS unit became operational in 2016 and is managed by Dr Martin Nyaga and administered through the office of the Dean, Faculty of Health Sciences, under the leadership of Prof Gert Van Zyl. Dr Nyaga has vast experience in microbial genomics, having done his PhD in Molecular Virology.

He has worked and collaborated with globally recognised centres of excellence in Prokaryotic and Eukaryotic genomics, namely the J. Craig Venter Institute and the Laboratory of Viral Metagenomics, Rega Institute, among others.

The unit has undertaken several projects and successfully generated data on bacterial, viral and human genomes. Currently, work is ongoing on bacterial and fungal metagenomics studies through 16S rRNA sequencing.

In addition, the unit is also working on plasmid/insert sequencing and whole genome sequencing of animal and human rotaviruses. The unit has capacity to undertake other kinds of panels like the HLA, Pan-cancer and Tumor 15 sequencing, among others.

Several investigators from the UFS including but not limited to Prof Felicity Burt, Prof Wijnand Swart, Dr Frans O’Neil, Dr Trudi O'Neill, Dr Charlotte Boucher, Dr Marieka Gryzenhout and Dr Kamaldeen Baba are actively in collaboration with the NGS unit.

The unit has also invested in other specialised equipment such as the M220 Focused-ultrasonicator (Covaris), 2100 Bioanalyzer system (Agilent) and the real-time PCR cycler, the Rotor-Gene Q (Qiagen), which both the UFS and external investigators can use for their research.

Investigators working on molecular and related studies are encouraged to engage with Dr Nyaga on how they would like to approach their genomics projects at the UFS NGS unit. 

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