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27 June 2023 | Story Department of Communication and Marketing | Photo Charl Devenish
Dr Abraham Matamanda and Prof Lochner Marais
UFS researchers, Dr Abraham R Matamanda, Senior Lecturer in the Department of Geography, and Prof Lochner Marais, Head of the UFS Centre for Development Support, collaborated with researchers in the UK and Brazil on a study on the impact of COVID-19 on children and young people. The study is part of the international PANEX-Youth research project.

Researchers from South Africa, the UK, and Brazil recently conducted a study on the impact of COVID-19 on children and young people, particularly those from disadvantaged households. Their research highlights that the pandemic has deepened existing inequalities, with children and young people’s voices and needs not being considered in policy decisions.

The study conducted by researchers from the University of the Free State (UFS) and the University of Fort Hare in South Africa; the University College London, the University of Birmingham, and Nottingham Trent University in the UK; and the University of São Paulo in Brazil, found that pandemic policy decisions largely ignored young people’s needs, resulting in long-term losses.

Educational inequalities

The report, titled International and National Overviews of the impact of COVID-19 on Education, Food and Play/Leisure and Related Adaptations, outlines how slow government action and policy gaps in efforts to stop the spread of COVID-19 have had a negative impact on children and young people’s health and welfare.

South Africa has been one of the countries hardest hit by COVID-19, and the study shows that due to social isolation and economic disruption caused by lockdowns, children and young people’s education has been stunted, their access to nutritious food has been reduced, and their ability to develop socially through play has been significantly restricted. The impact was worst for those living in disadvantaged poor households.

The study, which is part of the first stage of the PANEX-Youth research project, is divided into two volumes: the ‘Long Report’, highlighting the wider impact of the pandemic on children across the world, while the ‘Short Report’ drills down on the impact on three countries, namely the UK, South Africa, and Brazil.

Further insights from the study show that the digital divide has compounded educational inequalities as education has moved online during the pandemic, with households and regions with insufficient internet access falling behind. Collectively, and combined with the continuing cost-of-living crisis, the researchers believe that these disadvantages are likely to have detrimental consequences for children and young people in the short and long term, with many not yet visible.

Future pandemic planning

The team – which includes UFS researchers, Dr Abraham R Matamanda, Senior Lecturer in the Department of Geography, and Prof Lochner Marais, Head of the UFS Centre for Development Support – expects that policy gaps during the pandemic will negatively impact young people’s professional life trajectories, healthy lifestyles, mental well-being, educational opportunities, and self-confidence.

The team put together five recommendations to ensure that children’s well-being is incorporated into any future pandemic planning. These suggestions include:

  • The need to keep children and young people at the centre of pandemic preparedness efforts.
  • More priority and attention given to the hidden voices and experiences of young people, and particularly those from monetary poor households.
  • Greater recognition that schools play an important, central role as life and care hubs.
  • Greater recognition of play and leisure as rights that are fundamental to children and young people’s development.
  • More structured and systemic responses to multiple dimensions of risk from local and national responses are recommended, based on a rigorous assessment of what worked and failed during the pandemic.

Adapting in the post-pandemic period

Prof Lauren Andres, Professor of Planning and Urban Transformations at the University College London – also the lead author of the report – said: “COVID-19 exposed and exacerbated inequalities that already existed prior to the pandemic. Children and young people’s voices and needs were not heard and accounted for. Our research shows that because of policy gaps and slow government action during the pandemic, disadvantaged children and young people are now facing serious consequences that could be with them for a long time, both here in the UK and around the world.”

According to Dr Matamanda, “The COVID-19 pandemic showed the lack of understanding of what children and young people need in their daily lives. During the pandemic, the rights of children and young people, especially play/leisure, accessing adequate food and education, seemed to be overlooked or least prioritised. This was evident from the slow and inconsistent COVID-19 government policies and strategies that failed to acknowledge the networks and value chains through which children and young people are supported. In this way, our research shows the gaps and inequalities created and widened among children and young people in South Africa, especially those from disadvantaged households who have now been left behind and are grappling to adapt in the post-pandemic period.”

Read the full report here: https://panexyouth.com/

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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