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18 April 2024 | Story Andre Damons | Photo Charl Devenish
Dr Osayande Evbuomwan
Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine at the University of the Free State (UFS), received the first clinical PhD in nuclear medicine completed at the UFS at the April graduation ceremonies.

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS), graduated with the first clinical PhD in nuclear medicine completed at the UFS.

He graduated on Thursday (18 April 2024) at the university’s autumn graduation ceremonies when the Faculty of Health Sciences conferred degrees on its graduation class of 2024.

Dr Evbuomwan, the man behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy and now Actinium 225 PSMA therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer, said his PhD is about using a special radiopharmaceutical called Technetium 99m ECDG to detect active disease in the joints of patients with rheumatoid arthritis (RA).

More opportunities for similar degrees

This research has won him the Society of Nuclear Medicine and Molecular Imaging (SNMMI) International Best Abstract Award for South Africa during last year’s SNMMI 2023 Annual Meeting in the US.

“I am very grateful, and at the same time, proud about this achievement (his PhD). This qualification will definitely give more opportunities for further similar degrees at the department. So yes, I feel very happy and fulfilled.

“Rheumatoid arthritis is a debilitating disease with associated morbidity that can lead to serious joint deformity and destruction. The need for an investigation with a very high diagnostic accuracy in detecting active disease is needed, especially in the detection of subclinical disease. Few prior studies in the literature had shown promising results with Tc 99m ECDG imaging in this regard. So, we decided to conduct a proper prospective study to test this hypothesis,” says Dr Evbuomwan.

This research, he explains, was also aimed at finding out if the new nuclear medicine radiopharmaceutical for the identification of active disease in patients with rheumatoid arthritis can also offer prognostic information. This aspect of the study concluded that this particular radiopharmaceutical (Tc – 99m ECDG) is highly sensitive in identifying synovitis (inflammation of the membrane that protects joints) and is capable of offering prognostic information in patients with rheumatoid arthritis.

This was the first prospective study to assess the prognostic value of this radiopharmaceutical in patients with rheumatoid arthritis, Dr Evbuomwan says.

Researching theranostics in the future

According to him, he had a smooth journey to completing his PhD – something he contributes to support from the fantastic team of three supervisors, the assistant who prepared the radiopharmaceutical, the rheumatology department, the radiographers and nurses at the Department of Nuclear Medicine, and most importantly, his wife and two daughters.

His passion for research, growth and the practice of nuclear medicine were his major motivators on this journey.

Dr Evbuomwan is currently looking at the possibility of starting research on theranostics. The only stumbling block for now, he says, is that the department still does not have a PET/CT camera, as this is very vital in today’s nuclear medicine practice. However, together with the Free State Department of Health, they are working hard to secure one.

“I now want to focus on nuclear medicine therapy and its promotion. This includes both imaging and treatment (theranostics) of certain cancers, most especially prostate cancer, neuroendocrine neoplasms, thyroid cancers and the neuroectodermal tumours. I also want to focus on being involved with the training of more registrars at the department of nuclear medicine and increasing the awareness of nuclear medicine amongst colleagues in the Free State,” says Dr Evbuomwan about his future plans. 

News Archive

Giraffe research broadcast on National Geographic channel
2016-03-09

Description: Giraffe research  Tags: Giraffe research

A documentary focusing on the latest and most interesting research about giraffes was recently broadcasted on National Geographic. Dr Francois Deacon from the UFS Department of Animal, Wildlife and Grassland Sciences and the team of researchers working with him, were first in the world to equip giraffes with GPS collars, and to conduct research on them.

Research by Dr Francois Deacon, from the UFS Department of Animal, Wildlife and Grassland Sciences, involving the equipping of giraffes with GPS collars, was broadcast this week as part of a documentary (4 March 2016 and subsequent weeks) on National Geographic (Channel 182). The documentary is the first of two on his team's research.

Dr Deacon and the team of researchers working with him were the first in the world to equip giraffes with GPS collars, and to conduct research on this initiative. The group of researchers can now follow the animals night and day by means of the GPS collars, while monitoring their movements from a distance on a computer screen and seeing the world from a giraffe's perspective.

“The documentary focuses on the latest and interesting information about our research in different countries,” Dr Deacon said. Besides their local research on giraffes, he and his team also assist in other projects and research in Namibia, Botswana, Zambia, Kenya, the Democratic Republic of the Congo, and Uganda.

“There is much to learn from the documentary,” Dr Deacon said. Interesting facts from their research include herd interactions by individuals towards each other, bulls versus bulls, and cows versus calves. In the documentary, the viewer can also learn how giraffes use thermoregulation, their tongues, and roaming areas and distances; peculiar behaviour such as feeding on bones and soil; bulls fighting; how and when giraffes drink water; and the conservation and management of giraffes.
 
Focus is also placed on the manner in which the latest research plays a role in the better understanding of the animals.
 
According to Dr Deacon, this is the first documentary to focus on giraffe research on such a large scale. Marco Polo Films from Terra Mater are contracted by National Geographic to produce nature films – this was the hundredth nature film produced by them.
 
“There has never before been such a production about giraffes. It also attracted huge interest and reaction overseas, which will provide great exposure for our research and for the UFS.
 
“We believe that the media involvement will provide much more exposure to giraffes, which is a good thing, since they are facing extinction in Africa. The exposure can, in itself, lead to new research and has already started attracting international students to the UFS,” Dr Deacon said.
 
The second documentary will follow later this year. Iniosante, a film team from Texas, USA, is producing this film, which focuses on the extinction of giraffes. It is the same team responsible for the production Last of the Longnecks.



Additional resources:


-    Last of the Longnecks (trailer)
-    Giraffe – Up high and personal (National Geographic video)
-    Giraffe: African Giant (National Geographic video)
-    Giraffe – Up high and personal (article)

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